Utilisation of Real-world Data from Heart Failure Registries in OECD Countries - A Systematic Review

Overview

Journal Int J Cardiol Heart Vasc

Date 2018 Jun 30

PMID 29955668

Citations 8

Authors

Xiaoyang Du

Adina Khamitova

Mattias Kyhlstedt

Sun Sun

Mathilde Sengoelge

Affiliations

Soon will be listed here.

Abstract

Background: Heart failure represents a major public health issue that impacts 26 million people globally. Currently, real-world data represents a key instrument for providing the verification of both internal and external validity, yet there is still a lack of understanding regarding its scope in complementing evidence of treatments for heart failure. This study aims to increase understanding of the utilisation of real-word data from heart failure registries in Organisation for Economic Co-operation and Development (OECD) countries.

Method: This was a systematic review of existing observational studies from heart failure registries in 35 OECD member countries. Studies from 2000 to March 2017 were identified through electronic databases (MEDLINE (Ovid), EMBASE, Web of Science Core Collection, CINAHL (Ebsco), Cochrane CENTRAL) and appraised according to eligibility criteria.

Results: Two-hundred and two studies met the inclusion criteria, in which the majority were published from 2013 to 2016. All 202 studies were observational, among which 98% were cohort studies (198). The median sample size of all studies was 5152 (2417 to 32,890) and median study period 55 months (33.0 to 72.0). Swedish heart failure registry had the most publications (24, 12%).

Conclusion: Since 2000 there has been an upward trend in the number of published observational studies on heart failure registries in OECD countries with increasingly diverse outcomes and advanced statistical methods to improve their validity and reliability. This indicates that the utilisation of real-world data has experienced a significant upsurge in complementing the findings of clinical trials for improved research of heart failure treatments.

Citing Articles

Identification and Mapping Real-World Data Sources for Heart Failure, Acute Coronary Syndrome, and Atrial Fibrillation.

Studer R, Sartini C, Suzart-Woischnik K, Agrawal R, Natani H, Gill S Cardiology. 2021; 147(1):98-106.

PMID: 34781301 PMC: 8985014. DOI: 10.1159/000520674.

Part 1: The Wider Considerations in Translating Heart Failure Guidelines.

Iyngkaran P, Wilson A, Wong J, Prior D, Kaye D, Hare D Curr Cardiol Rev. 2021; 17(5):e160721190003.

PMID: 33423650 PMC: 8950449. DOI: 10.2174/1573403X16666210108104945.

Impact of sex differences in co-morbidities and medication adherence on outcome in 25 776 heart failure patients.

Gurgoze M, van der Galien O, Limpens M, Roest S, Hoekstra R, IJpma A ESC Heart Fail. 2020; 8(1):63-73.

PMID: 33247631 PMC: 7835621. DOI: 10.1002/ehf2.13113.

Perioperative Sleep Disturbances and Postoperative Delirium in Adult Patients: A Systematic Review and Meta-Analysis of Clinical Trials.

Wang H, Zhang L, Zhang Z, Li Y, Luo Q, Yuan S Front Psychiatry. 2020; 11:570362.

PMID: 33173517 PMC: 7591683. DOI: 10.3389/fpsyt.2020.570362.

Regional registries on the management of atrial fibrillation: Essential pieces in the global puzzle.

Gumprecht J, Lip G, Potpara T Int J Cardiol Heart Vasc. 2020; 26:100473.

PMID: 32142061 PMC: 7046532. DOI: 10.1016/j.ijcha.2020.100473.

References

Oyinlola J, Campbell J, Kousoulis A . Is real world evidence influencing practice? A systematic review of CPRD research in NICE guidances. BMC Health Serv Res. 2016; 16:299. PMC: 4960862. DOI: 10.1186/s12913-016-1562-8. View

Trullas J, Miro O, Formiga F, Martin-Sanchez F, Montero-Perez-Barquero M, Jacob J . The utility of heart failure registries: a descriptive and comparative study of two heart failure registries. Postgrad Med J. 2016; 92(1087):260-6. DOI: 10.1136/postgradmedj-2015-133739. View

Hu C, Xing Y, Cormier J, Chang G . Assessing the utility of cancer-registry-processed cause of death in calculating cancer-specific survival. Cancer. 2013; 119(10):1900-7. PMC: 3673539. DOI: 10.1002/cncr.27968. View

Bolli R, Chugh A, DAmario D, Loughran J, Stoddard M, Ikram S . Cardiac stem cells in patients with ischaemic cardiomyopathy (SCIPIO): initial results of a randomised phase 1 trial. Lancet. 2011; 378(9806):1847-57. PMC: 3614010. DOI: 10.1016/S0140-6736(11)61590-0. View

Garrison Jr L, Neumann P, Erickson P, Marshall D, Daniel Mullins C . Using real-world data for coverage and payment decisions: the ISPOR Real-World Data Task Force report. Value Health. 2007; 10(5):326-35. DOI: 10.1111/j.1524-4733.2007.00186.x. View

Mahajan R . Real world data: Additional source for making clinical decisions. Int J Appl Basic Med Res. 2015; 5(2):82. PMC: 4456898. DOI: 10.4103/2229-516X.157148. View

Hoque D, Kumari V, Hoque M, Ruseckaite R, Romero L, Evans S . Impact of clinical registries on quality of patient care and clinical outcomes: A systematic review. PLoS One. 2017; 12(9):e0183667. PMC: 5591016. DOI: 10.1371/journal.pone.0183667. View

Sterne J, Hernan M, Reeves B, Savovic J, Berkman N, Viswanathan M . ROBINS-I: a tool for assessing risk of bias in non-randomised studies of interventions. BMJ. 2016; 355:i4919. PMC: 5062054. DOI: 10.1136/bmj.i4919. View

Maggioni A, van Gool K, Biondi N, Urso R, Klazinga N, Ferrari R . Appropriateness of Prescriptions of Recommended Treatments in Organisation for Economic Co-operation and Development Health Systems: Findings Based on the Long-Term Registry of the European Society of Cardiology on Heart Failure. Value Health. 2015; 18(8):1098-104. DOI: 10.1016/j.jval.2015.08.005. View

10.

Ouzzani M, Hammady H, Fedorowicz Z, Elmagarmid A . Rayyan-a web and mobile app for systematic reviews. Syst Rev. 2016; 5(1):210. PMC: 5139140. DOI: 10.1186/s13643-016-0384-4. View

11.

Agha R, Cooper D, Muir G . The reporting quality of randomised controlled trials in surgery: a systematic review. Int J Surg. 2007; 5(6):413-22. DOI: 10.1016/j.ijsu.2007.06.002. View

12.

Ponikowski P, Anker S, Alhabib K, Cowie M, Force T, Hu S . Heart failure: preventing disease and death worldwide. ESC Heart Fail. 2017; 1(1):4-25. DOI: 10.1002/ehf2.12005. View

13.

Moher D, Liberati A, Tetzlaff J, Altman D . Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. PLoS Med. 2009; 6(7):e1000097. PMC: 2707599. DOI: 10.1371/journal.pmed.1000097. View

14.

Liberati A, Altman D, Tetzlaff J, Mulrow C, Gotzsche P, Ioannidis J . The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate health care interventions: explanation and elaboration. PLoS Med. 2009; 6(7):e1000100. PMC: 2707010. DOI: 10.1371/journal.pmed.1000100. View

15.

Hickey G, Grant S, Cosgriff R, Dimarakis I, Pagano D, Kappetein A . Clinical registries: governance, management, analysis and applications. Eur J Cardiothorac Surg. 2013; 44(4):605-14. DOI: 10.1093/ejcts/ezt018. View

16.

Christ M, Stork S, Dorr M, Heppner H, Muller C, Wachter R . Heart failure epidemiology 2000-2013: insights from the German Federal Health Monitoring System. Eur J Heart Fail. 2016; 18(8):1009-18. DOI: 10.1002/ejhf.567. View

17.

Berger M, Lipset C, Gutteridge A, Axelsen K, Subedi P, Madigan D . Optimizing the leveraging of real-world data to improve the development and use of medicines. Value Health. 2015; 18(1):127-30. DOI: 10.1016/j.jval.2014.10.009. View

18.

Wollert K, Meyer G, Lotz J, Ringes-Lichtenberg S, Lippolt P, Breidenbach C . Intracoronary autologous bone-marrow cell transfer after myocardial infarction: the BOOST randomised controlled clinical trial. Lancet. 2004; 364(9429):141-8. DOI: 10.1016/S0140-6736(04)16626-9. View

19.

Montero-Perez-Barquero M, Manzano L, Formiga F, Roughton M, Coats A, Rodriguez-Artalejo F . Utility of the SENIORS elderly heart failure risk model applied to the RICA registry of acute heart failure. Int J Cardiol. 2015; 182:449-53. DOI: 10.1016/j.ijcard.2014.12.173. View

20.

. European Society of Cardiology Heart Failure Long-Term Registry (ESC-HF-LT): 1-year follow-up outcomes and differences across regions. Eur J Heart Fail. 2017; 19(3):438. DOI: 10.1002/ejhf.772. View