[Alpha-Gal-associated Delayed Red Meat Anaphylaxis As an Occupational Disease]

Overview

Journal Hautarzt

Specialty Dermatology

Date 2018 Jun 29

PMID 29951852

Citations 3

Authors

W Anemuller

M Mohr

R Brans

A Homann

U Jappe

Affiliations

Soon will be listed here.

Abstract

In a 30-year-old chef with recurrent delayed angioedema history as well as the experimental detection of IgE antibodies against galactose-alpha-(1,3)-galactose (alpha-Gal) pointed to alpha-Gal as the causative agent. The diagnosis, therefore, was delayed anaphylaxis due to alpha-Gal. Because of the potential relationship to his profession, we submitted a dermatologist's report BK 5101 to the liability and insurance association, whereupon his contract of employment was terminated without notice. As a consequence, we reported an occupational disease. This case demonstrates an underdiagnosed, potentially life-threatening allergy to the disaccharide alpha-Gal in red meat as an occupational disease.

Citing Articles

Occupational anaphylaxis: A Position Paper of the German Society of Allergology and Clinical Immunology (DGAKI).

Treudler R, Worm M, Bauer A, Dickel H, Heine G, Jappe U Allergol Select. 2024; 8:407-424.

PMID: 39659712 PMC: 11629776. DOI: 10.5414/ALX02543E.

Current and Future Strategies for the Diagnosis and Treatment of the Alpha-Gal Syndrome (AGS).

Vaz-Rodrigues R, Mazuecos L, de la Fuente J J Asthma Allergy. 2022; 15:957-970.

PMID: 35879928 PMC: 9307871. DOI: 10.2147/JAA.S265660.

Update of the S2k guideline on the management of IgE-mediated food allergies.

Worm M, Reese I, Ballmer-Weber B, Beyer K, Bischoff S, Bohle B Allergol Select. 2021; 5:195-243.

PMID: 34263109 PMC: 8276640. DOI: 10.5414/ALX02257E.

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