Transcatheter Aortic Valve Implantation in Germany

Overview

Journal Clin Res Cardiol

Specialty Cardiology & Vascular Diseases

Date 2018 Jun 29

PMID 29951801

Citations 12

Authors

Won-Keun Kim

Christian W Hamm

Affiliations

Soon will be listed here.

Abstract

Over the past years, there has been a tremendous evolution of transcatheter aortic valve implantation (TAVI) that turned a novel revolutionary approach to a mature concept. Peri-procedural complications and mortality rates have markedly decreased; hence, TAVI became an integral component of the treatment strategy for patients with severe aortic stenosis and now is the preferred therapy in elderly patients with moderate to high or prohibitive operative risk. This successful development would not have been possible without the joint efforts of clinicians, scientists, engineers, and many others from around the world. In this context, Germany has been one of the forerunners in implanting transcatheter heart valves, as evidenced not only by the high numbers of procedures, but in particular by some individual pioneering achievements. Here, we picture German contributions in the field of TAVI that had impact on clinical practice, including first-in-man experience, CE mark trials, randomized studies, large registries, and other procedurally relevant aspects.

Citing Articles

Short-Term Changes in Arterial Stiffness Measured by 2D Speckle Tracking in Patients Undergoing Transcatheter Aortic Valve Implantation.

Arnold L, Haas N, Jakob A, Fischer J, Massberg S, Deseive S J Clin Med. 2024; 13(1).

PMID: 38202229 PMC: 10779940. DOI: 10.3390/jcm13010222.

Microcirculatory tissue oxygenation correlates with kidney function after transcatheter aortic valve implantation-Results from a prospective observational study.

Dietrich M, Antonovici A, Holle T, Nusshag C, Kapp A, Studier-Fischer A Front Cardiovasc Med. 2023; 10:1108256.

PMID: 36865886 PMC: 9971913. DOI: 10.3389/fcvm.2023.1108256.

Artificial Intelligence-Based Spiral CT 3D Reconstruction in Transcatheter Aortic Valve Implantation.

Zhang K, Gao Y, Lv J, Li J, Liu J Comput Math Methods Med. 2022; 2022:5794681.

PMID: 35572825 PMC: 9095377. DOI: 10.1155/2022/5794681.

[Frailty as potential indicator of perioperative risk for older patients].

Derwall M, Coburn M Anaesthesist. 2019; 69(3):151-158.

PMID: 31802172 DOI: 10.1007/s00101-019-00699-0.

Periprocedural embolisation of a Sapien 3 TAVI prosthesis: failure and success.

Krapf S, von Scheidt W, Thilo C Clin Res Cardiol. 2019; 109(5):649-651.

PMID: 31784902 DOI: 10.1007/s00392-019-01573-0.

References

Ghanem A, Muller A, Nahle C, Kocurek J, Werner N, Hammerstingl C . Risk and fate of cerebral embolism after transfemoral aortic valve implantation: a prospective pilot study with diffusion-weighted magnetic resonance imaging. J Am Coll Cardiol. 2010; 55(14):1427-32. DOI: 10.1016/j.jacc.2009.12.026. View

Wenaweser P, Buellesfeld L, Gerckens U, Grube E . Percutaneous aortic valve replacement for severe aortic regurgitation in degenerated bioprosthesis: the first valve in valve procedure using the Corevalve Revalving system. Catheter Cardiovasc Interv. 2007; 70(5):760-4. DOI: 10.1002/ccd.21300. View

Walther T, Falk V, Borger M, Dewey T, Wimmer-Greinecker G, Schuler G . Minimally invasive transapical beating heart aortic valve implantation--proof of concept. Eur J Cardiothorac Surg. 2006; 31(1):9-15. DOI: 10.1016/j.ejcts.2006.10.034. View

Eggebrecht H, Vaquerizo B, Moris C, Bossone E, Lammer J, Czerny M . Incidence and outcomes of emergent cardiac surgery during transfemoral transcatheter aortic valve implantation (TAVI): insights from the European Registry on Emergent Cardiac Surgery during TAVI (EuRECS-TAVI). Eur Heart J. 2017; 39(8):676-684. DOI: 10.1093/eurheartj/ehx713. View

Naber C, Ghanem A, Abizaid A, Wolf A, Sinning J, Werner N . First-in-man use of a novel embolic protection device for patients undergoing transcatheter aortic valve implantation. EuroIntervention. 2012; 8(1):43-50. DOI: 10.4244/EIJV8I1A8. View

Gaede L, Blumenstein J, Liebetrau C, Dorr O, Kim W, Nef H . Outcome after transvascular transcatheter aortic valve implantation in 2016. Eur Heart J. 2017; 39(8):667-675. PMC: 5837346. DOI: 10.1093/eurheartj/ehx688. View

Abdel-Wahab M, Neumann F, Mehilli J, Frerker C, Richardt D, Landt M . 1-Year Outcomes After Transcatheter Aortic Valve Replacement With Balloon-Expandable Versus Self-Expandable Valves: Results From the CHOICE Randomized Clinical Trial. J Am Coll Cardiol. 2015; 66(7):791-800. DOI: 10.1016/j.jacc.2015.06.026. View

Kahlert P, Knipp S, Schlamann M, Thielmann M, Al-Rashid F, Weber M . Silent and apparent cerebral ischemia after percutaneous transfemoral aortic valve implantation: a diffusion-weighted magnetic resonance imaging study. Circulation. 2010; 121(7):870-8. DOI: 10.1161/CIRCULATIONAHA.109.855866. View

Falk V, Walther T, Schwammenthal E, Strauch J, Aicher D, Wahlers T . Transapical aortic valve implantation with a self-expanding anatomically oriented valve. Eur Heart J. 2010; 32(7):878-87. DOI: 10.1093/eurheartj/ehq445. View

10.

Grube E, Schuler G, Buellesfeld L, Gerckens U, Linke A, Wenaweser P . Percutaneous aortic valve replacement for severe aortic stenosis in high-risk patients using the second- and current third-generation self-expanding CoreValve prosthesis: device success and 30-day clinical outcome. J Am Coll Cardiol. 2007; 50(1):69-76. DOI: 10.1016/j.jacc.2007.04.047. View

11.

Kahlert P, Al-Rashid F, Dottger P, Mori K, Plicht B, Wendt D . Cerebral embolization during transcatheter aortic valve implantation: a transcranial Doppler study. Circulation. 2012; 126(10):1245-55. DOI: 10.1161/CIRCULATIONAHA.112.092544. View

12.

Hamm C, Mollmann H, Holzhey D, Beckmann A, Veit C, Figulla H . The German Aortic Valve Registry (GARY): in-hospital outcome. Eur Heart J. 2013; 35(24):1588-98. PMC: 4065384. DOI: 10.1093/eurheartj/eht381. View

13.

Mollmann H, Kim W, Kempfert J, Blumenstein J, Liebetrau C, Nef H . Transfemoral aortic valve implantation of Edwards SAPIEN XT without predilatation is feasible. Clin Cardiol. 2014; 37(11):667-71. PMC: 6649495. DOI: 10.1002/clc.22318. View

14.

Haussig S, Mangner N, Dwyer M, Lehmkuhl L, Lucke C, Woitek F . Effect of a Cerebral Protection Device on Brain Lesions Following Transcatheter Aortic Valve Implantation in Patients With Severe Aortic Stenosis: The CLEAN-TAVI Randomized Clinical Trial. JAMA. 2016; 316(6):592-601. DOI: 10.1001/jama.2016.10302. View

15.

Walther T, Hamm C, Schuler G, Berkowitsch A, Kotting J, Mangner N . Perioperative Results and Complications in 15,964 Transcatheter Aortic Valve Replacements: Prospective Data From the GARY Registry. J Am Coll Cardiol. 2015; 65(20):2173-80. DOI: 10.1016/j.jacc.2015.03.034. View

16.

Beckmann A, Hamm C, Figulla H, Cremer J, Kuck K, Lange R . The German Aortic Valve Registry (GARY): a nationwide registry for patients undergoing invasive therapy for severe aortic valve stenosis. Thorac Cardiovasc Surg. 2012; 60(5):319-25. DOI: 10.1055/s-0032-1323155. View

17.

Frerker C, Bestehorn K, Schluter M, Bestehorn M, Hamm C, Mollmann H . In-hospital mortality in propensity-score matched low-risk patients undergoing routine isolated surgical or transfemoral transcatheter aortic valve replacement in 2014 in Germany. Clin Res Cardiol. 2017; 106(8):610-617. DOI: 10.1007/s00392-017-1097-y. View

18.

Walther T, Falk V, Borger M, Kempfert J, Ender J, Linke A . Transapical aortic valve implantation in patients requiring redo surgery. Eur J Cardiothorac Surg. 2009; 36(2):231-4. DOI: 10.1016/j.ejcts.2009.02.016. View

19.

Eggebrecht H, Bestehorn M, Haude M, Schmermund A, Bestehorn K, Voigtlander T . Outcomes of transfemoral transcatheter aortic valve implantation at hospitals with and without on-site cardiac surgery department: insights from the prospective German aortic valve replacement quality assurance registry (AQUA) in 17 919 patients. Eur Heart J. 2016; 37(28):2240-8. DOI: 10.1093/eurheartj/ehw190. View

20.

Kempfert J, Treede H, Rastan A, Schonburg M, Thielmann M, Sorg S . Transapical aortic valve implantation using a new self-expandable bioprosthesis (ACURATE TA™): 6-month outcomes. Eur J Cardiothorac Surg. 2012; 43(1):52-6. DOI: 10.1093/ejcts/ezs139. View