» Articles » PMID: 29941854

Acupuncture and Neural Mechanism in the Management of Low Back Pain-An Update

Overview
Specialty Pharmacology
Date 2018 Jun 27
PMID 29941854
Citations 28
Authors
Affiliations
Soon will be listed here.
Abstract

Within the last 10 years, the percentage of low back pain (LBP) prevalence increased by 18%. The management and high cost of LBP put a tremendous burden on the healthcare system. Many risk factors have been identified, such as lifestyle, trauma, degeneration, postural impairment, and occupational related factors; however, as high as 95% of the cases of LBP are non-specific. Currently, LBP is treated pharmacologically. Approximately 25 to 30% of the patients develop serious side effects, such as drowsiness and drug addiction. Spinal surgery often does not result in a massive improvement of pain relief. Therefore, complementary approaches are being integrated into the rehabilitation programs. These include chiropractic therapy, physiotherapy, massage, exercise, herbal medicine and acupuncture. Acupuncture for LBP is one of the most commonly used non-pharmacological pain-relieving techniques. This is due to its low adverse effects and cost-effectiveness. Currently, many randomized controlled trials and clinical research studies have produced promising results. In this article, the causes and incidence of LBP on global health care are reviewed. The importance of treatment by acupuncture is considered. The efforts to reveal the link between acupuncture points and anatomical features and the neurological mechanisms that lead to acupuncture-induced analgesic effect are reviewed.

Citing Articles

Ultrasound-guided drug injection combined with mini-needle knife therapy for acute lumbar sprain: a prospective interventional study.

Xiao Y, Zhang Y, Li S, Long X, Su Y, Zeng Z Eur J Orthop Surg Traumatol. 2025; 35(1):108.

PMID: 40067511 DOI: 10.1007/s00590-025-04234-3.


Traditional Chinese medicine as a protective strategy against chemotherapy-induced cardiotoxicity: An overview of the literature.

Wang J, Shao H, Zhang Y, Ge T, Chen X, Mou X J Tradit Complement Med. 2025; 15(2):107-118.

PMID: 40060147 PMC: 11883632. DOI: 10.1016/j.jtcme.2024.06.010.


Effectiveness of Self-Tennis Ball Massage Therapy on Low Back Pain Among Geriatric Individuals.

Salvi S, Londhe N Cureus. 2025; 17(2):e78467.

PMID: 40051941 PMC: 11883332. DOI: 10.7759/cureus.78467.


Spatial Distribution Dynamics of Sensory Disturbances in the Treatment of Obesity-Related Meralgia Paresthetica Using Transcutaneous Electrical Nerve Stimulation.

Al-Zamil M, Kulikova N, Shnayder N, Korchazhkina N, Petrova M, Mansur N J Clin Med. 2025; 14(2).

PMID: 39860396 PMC: 11765708. DOI: 10.3390/jcm14020390.


Peri-articular Dextrose Prolotherapy: Investigating the Effect of Injection Site on Knee Osteoarthritis Pain: A Double-Blind, Randomized, Clinical Trial.

Ebnerasooli S, Barghi A, Nasseri K, Moghimi N Anesth Pain Med. 2024; 14(2):e140966.

PMID: 39411379 PMC: 11473996. DOI: 10.5812/aapm-140966.


References
1.
Salzberg L, Manusov E . Management options for patients with chronic back pain without an etiology. Health Serv Insights. 2014; 6:33-8. PMC: 4089831. DOI: 10.4137/HSI.S10469. View

2.
Ren W, Tu W, Jiang S, Cheng R, Du Y . Electroacupuncture improves neuropathic pain: Adenosine, adenosine 5'-triphosphate disodium and their receptors perhaps change simultaneously. Neural Regen Res. 2014; 7(33):2618-23. PMC: 4200729. DOI: 10.3969/j.issn.1673-5374.2012.33.007. View

3.
Goldman N, Chen M, Fujita T, Xu Q, Peng W, Liu W . Adenosine A1 receptors mediate local anti-nociceptive effects of acupuncture. Nat Neurosci. 2010; 13(7):883-8. PMC: 3467968. DOI: 10.1038/nn.2562. View

4.
Daghighi M, Pouriesa M, Maleki M, Fouladi D, Pezeshki M, Mazaheri Khameneh R . Migration patterns of herniated disc fragments: a study on 1,020 patients with extruded lumbar disc herniation. Spine J. 2013; 14(9):1970-7. DOI: 10.1016/j.spinee.2013.11.056. View

5.
Maatta J, Wadge S, MacGregor A, Karppinen J, Williams F . ISSLS Prize Winner: Vertebral Endplate (Modic) Change is an Independent Risk Factor for Episodes of Severe and Disabling Low Back Pain. Spine (Phila Pa 1976). 2015; 40(15):1187-93. DOI: 10.1097/BRS.0000000000000937. View