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IgA Nephropathy: New Insights into the Role of Complement

Overview
Journal Kidney Int
Publisher Elsevier
Specialty Nephrology
Date 2018 Jun 24
PMID 29933843
Citations 28
Authors
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Abstract

Glomerular complement deposition is common in IgA nephropathy, and recent genome-wide association studies point to a role of complement factor H and complement factor H-related proteins in disease susceptibility. A number of recent studies have now documented elevated levels of some factor H-related proteins in IgA nephropathy, which might contribute to enhanced complement activation.

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