Toxins and Their Molecular Activity in Infectious Diseases

Overview

Journal Toxins (Basel)

Publisher MDPI

Specialty Toxicology

Date 2018 Jun 21

PMID 29921792

Citations 154

Authors

Diana Oliveira

Anabela Borges

Manuel Simoes

Affiliations

Soon will be listed here.

Abstract

is a microorganism resident in the skin and nasal membranes with a dreadful pathogenic potential to cause a variety of community and hospital-acquired infections. The frequency of these infections is increasing and their treatment is becoming more difficult. The ability of to form biofilms and the emergence of multidrug-resistant strains are the main reasons determining the challenge in dealing with these infections. infectious capacity and its success as a pathogen is related to the expression of virulence factors, among which the production of a wide variety of toxins is highlighted. For this reason, a better understanding of toxins is needed to enable the development of new strategies to reduce their production and consequently improve therapeutic approaches. This review focuses on understanding the toxin-based pathogenesis of and their role on infectious diseases.

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