Stem Cells Technology: a Powerful Tool Behind New Brain Treatments

Overview

Journal Drug Deliv Transl Res

Publisher Springer

Specialty Pharmacology

Date 2018 Jun 20

PMID 29916013

Citations 2

Authors

Lucienne N Duru

Zhenzhen Quan

Talal Jamil Qazi

Hong Qing

Affiliations

Soon will be listed here.

Abstract

Stem cell research has recently become a hot research topic in biomedical research due to the foreseen unlimited potential of stem cells in tissue engineering and regenerative medicine. For many years, medicine has been facing intense challenges, such as an insufficient number of organ donations that is preventing clinicians to fulfill the increasing needs. To try and overcome this regrettable matter, research has been aiming at developing strategies to facilitate the in vitro culture and study of stem cells as a tool for tissue regeneration. Meanwhile, new developments in the microfluidics technology brought forward emerging cell culture applications that are currently allowing for a better chemical and physical control of cellular microenvironment. This review presents the latest developments in stem cell research that brought new therapies to the clinics and how the convergence of the microfluidics technology with stem cell research can have positive outcomes on the fields of regenerative medicine and high-throughput screening. These advances will bring new translational solutions for drug discovery and will upgrade in vitro cell culture to a new level of accuracy and performance. We hope this review will provide new insights into the understanding of new brain treatments from the perspective of stem cell technology especially regarding regenerative medicine and tissue engineering.

Citing Articles

Neural stem cell transplantation alleviates functional cognitive deficits in a mouse model of tauopathy.

Zhang H, Yuan C, Liu K, Yang Q, Zhao J, Li H Neural Regen Res. 2021; 17(1):152-162.

PMID: 34100451 PMC: 8451553. DOI: 10.4103/1673-5374.314324.

The potential of induced pluripotent stem cells for discriminating neurodevelopmental disorders.

Stock R, Jeckel P, Kraushaar U, Wust R, Fallgatter A, Volkmer H Stem Cells Transl Med. 2020; 10(1):50-56.

PMID: 32864861 PMC: 7780807. DOI: 10.1002/sctm.20-0206.

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