A Sialoadenectomy is Associated with an Increased Risk of Coronary Heart Disease: A Three-year Follow-up Study

Overview

Journal PLoS One

Specialties General Medicine
Science

Date 2018 Jun 19

PMID 29912946

Citations 2

Authors

Shih-Han Hung

Chin-Hui Su

Herng-Ching Lin

Chung-Chien Huang

Senyeong Kao

Affiliations

Soon will be listed here.

Abstract

Little is known regarding the long-term adverse effects of a sialoadenectomy. The purpose of this study was to estimate the risk of coronary heart disease (CHD) among patients receiving a sialoadenectomy procedure by utilizing a cohort study based on a population-based database in Taiwan. This study retrieved data of the study sample from the Longitudinal Health Insurance Database 2005. This retrospective cohort study included 608 patients who underwent a sialoadenectomy and 1824 propensity score-matched comparison patients. We individually tracked each sampled patient for a 3-year period from their index date to discriminate those who subsequently received a diagnosis of CHD during the follow-up period. We found that respective incidence rates of CHD during the 3-year follow-up period were 3.87 (95% confidence interval (CI): 3.01-4.91) and 1.79 (95% CI: 1.45-2.18) per 100 person-years for patients who did and those who did not undergo a sialoadenectomy. The stratified Cox proportional analysis revealed that the hazard ratio of CHD during the 3-year follow-up period was 2.43 (95% CI: 1.77-3.33) than comparison patients. This study demonstrates an association between sialoadenectomy and CHD.

Citing Articles

Correction: A sialoadenectomy is associated with an increased risk of coronary heart disease: A three-year follow-up study.

Hung S, Su C, Lin H, Huang C, Kao S PLoS One. 2021; 16(1):e0243568.

PMID: 33417617 PMC: 7793256. DOI: 10.1371/journal.pone.0243568.

miR-185 silencing promotes the progression of atherosclerosis via targeting stromal interaction molecule 1.

Fang M, Li Y, Wu Y, Ning Z, Wang X, Li X Cell Cycle. 2019; 18(6-7):682-695.

PMID: 30784343 PMC: 6464577. DOI: 10.1080/15384101.2019.1580493.

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