Optical Coherence Tomography Angiography in Retinal Vein Occlusions

Overview

Journal Graefes Arch Clin Exp Ophthalmol

Specialty Ophthalmology

Date 2018 Jun 17

PMID 29907946

Citations 19

Authors

Qian Wang

Szy Yann Chan

Yanni Yan

Jingyan Yang

Wenjia Zhou

Jost B Jonas

Wen Bin Wei

Affiliations

Soon will be listed here.

Abstract

Purpose: To examine the vascular density in different retinal layers and in the choriocapillaris in eyes with retinal vein occlusions (RVO).

Methods: Applying optical coherence tomography angiography (OCTA), we examined patients with unilateral RVOs and normal individuals of a control group.

Results: The study group included 48 patients with unilateral RVO and the control group 17 normal individuals. Eyes affected by RVO as compared to the contralateral unaffected eyes (all P < 0.001), and the contralateral unaffected eyes as compared to the eyes of the control group (P < 0.05), showed a lower vessel density in the superficial and deep retinal layers in all regions except for the foveal region. Choriocapillaris density was lower (P < 0.001), foveal retinal thickness and subfoveal choroidal thickness (P < 0.001) were thicker, and the foveal avascular zone was larger (P = 0.003) in the RVO eyes than in the contralateral eyes. For 29 eyes undergoing OCTA and fluorescein angiography, two examiners independently rated the retinas to be ischemic in fluorescein angiography in 14 eyes and in OCTA in 9 of these 14 eyes.

Conclusions: Upon OCTA, unaffected eyes of patients with unilateral RVOs showed vascular abnormalities in the superficial and deep retinal layers when compared to those of healthy individuals.

Citing Articles

Central and Peripheral Changes in Retinal Vein Occlusion and Fellow Eyes in Ultra-Widefield Optical Coherence Tomography Angiography.

Zhao X, Zhao Q, Wang C, Meng L, Cheng S, Gu X Invest Ophthalmol Vis Sci. 2024; 65(2):6.

PMID: 38306106 PMC: 10851174. DOI: 10.1167/iovs.65.2.6.

Optical coherence tomography angiography for macular microvessels in ischemic branch retinal vein occlusion treated with conbercept: predictive factors for the prognosis.

Tang L, Sun G, Zhao Y, Yang T, Yao J Int J Ophthalmol. 2023; 16(12):2049-2055.

PMID: 38111937 PMC: 10700074. DOI: 10.18240/ijo.2023.12.18.

Optical Coherence Tomography Angiography in Retinal Vascular Disorders.

Ong C, Wong M, Cheong K, Zhao J, Teo K, Tan T Diagnostics (Basel). 2023; 13(9).

PMID: 37175011 PMC: 10178415. DOI: 10.3390/diagnostics13091620.

Comparison of widefield swept-source optical coherence tomography angiography with ultra-widefield fluorescein angiography for the evaluation of lesions in retinal vein occlusion.

Siying L, Qiaozhu Z, Xinyao H, Linqi Z, Mingwei Z, Jinfeng Q BMC Ophthalmol. 2022; 22(1):422.

PMID: 36344951 PMC: 9639280. DOI: 10.1186/s12886-022-02642-1.

Structural and Visual Changes in Branch Retinal Vein Occlusion Patients with Retinal Atrophy.

Li Z, Gu X, Song S, Yu X, Zhang P, Dai H J Ophthalmol. 2022; 2022:8945467.

PMID: 36035899 PMC: 9410836. DOI: 10.1155/2022/8945467.

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