Enantioselective Syntheses of Homopropargylic Alcohols Via Asymmetric Allenylboration
Overview
Chemistry
Affiliations
A chiral phosphoric acid catalyzed allenylboration reaction is reported. Homopropargyl alcohols with an internal alkyne unit were obtained in good yields with high enantioselectivities under the developed conditions.
Stereo- and Enantioselective Syntheses of ()-1,3-Butadienyl-2-carbinols via Brønsted Acid Catalysis.
Chen M Org Lett. 2025; 27(3):887-891.
PMID: 39786719 PMC: 11773566. DOI: 10.1021/acs.orglett.4c04663.
Highly Stereo- and Enantioselective Syntheses of δ-Alkyl-Substituted ()-Homoallylic Alcohols.
Chen M Org Lett. 2025; 27(2):612-617.
PMID: 39761521 PMC: 11744790. DOI: 10.1021/acs.orglett.4c04401.
Zhang Z, Chen M Org Lett. 2024; 26(47):10102-10107.
PMID: 39561401 PMC: 11613688. DOI: 10.1021/acs.orglett.4c03755.
Copper-Catalyzed Asymmetric Acylboration of 1,3-Butadienylboronate with Acyl Fluorides.
Gao S, Liu J, Troya D, Chen M Angew Chem Int Ed Engl. 2023; 62(43):e202304796.
PMID: 37712934 PMC: 11144059. DOI: 10.1002/anie.202304796.
Liu J, Gao S, Miliordos E, Chen M J Am Chem Soc. 2023; 145(36):19542-19553.
PMID: 37639380 PMC: 11144060. DOI: 10.1021/jacs.3c02595.