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Aptamer-Based Biosensors for Antibiotic Detection: A Review

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Specialty Biotechnology
Date 2018 Jun 13
PMID 29891818
Citations 65
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Abstract

Antibiotic resistance and, accordingly, their pollution because of uncontrolled usage has emerged as a serious problem in recent years. Hence, there is an increased demand to develop robust, easy, and sensitive methods for rapid evaluation of antibiotics and their residues. Among different analytical methods, the aptamer-based biosensors (aptasensors) have attracted considerable attention because of good selectivity, specificity, and sensitivity. This review gives an overview about recently-developed aptasensors for antibiotic detection. The use of various aptamer assays to determine different groups of antibiotics, like β-lactams, aminoglycosides, anthracyclines, chloramphenicol, (fluoro)quinolones, lincosamide, tetracyclines, and sulfonamides are presented in this paper.

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References
1.
Miao Y, Ren H, Gan N, Cao Y, Li T, Chen Y . Fluorescent aptasensor for chloramphenicol detection using DIL-encapsulated liposome as nanotracer. Biosens Bioelectron. 2016; 81:454-459. DOI: 10.1016/j.bios.2016.03.034. View

2.
Pfeiffer F, Mayer G . Selection and Biosensor Application of Aptamers for Small Molecules. Front Chem. 2016; 4:25. PMC: 4908669. DOI: 10.3389/fchem.2016.00025. View

3.
Guo W, Sun N, Qin X, Pei M, Wang L . A novel electrochemical aptasensor for ultrasensitive detection of kanamycin based on MWCNTs-HMIMPF6 and nanoporous PtTi alloy. Biosens Bioelectron. 2015; 74:691-7. DOI: 10.1016/j.bios.2015.06.081. View

4.
de-Los-Santos-Alvarez N, Lobo-Castanon M, Miranda-Ordieres A, Tunon-Blanco P . SPR sensing of small molecules with modified RNA aptamers: detection of neomycin B. Biosens Bioelectron. 2009; 24(8):2547-53. DOI: 10.1016/j.bios.2009.01.011. View

5.
Wang A, Zhao H, Chen X, Tan B, Zhang Y, Quan X . A colorimetric aptasensor for sulfadimethoxine detection based on peroxidase-like activity of graphene/nickel@palladium hybrids. Anal Biochem. 2017; 525:92-99. DOI: 10.1016/j.ab.2017.03.006. View