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The Role of Therapeutic Endoscopy in Patients With Cirrhosis-Related Causes of Gastrointestinal Bleeding

Overview
Specialty Gastroenterology
Date 2018 Jun 11
PMID 29886513
Citations 2
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Abstract

Purpose Of Review: This article aims to review current therapeutic endoscopic treatments available for the management of gastrointestinal bleeding related to cirrhosis.

Recent Findings: Endoscopic band ligation is an effective treatment for primary prophylaxis, acute bleeding, and secondary prophylaxis of esophageal varices as well as for acute bleeding and secondary prophylaxis of select gastric varices. Sclerotherapy is a treatment option for acute bleeding and secondary prophylaxis of esophageal varices when band ligation is technically difficult. Cyanoacrylate glue injection is an effective treatment for acute bleeding of gastric and ectopic varices. Argon plasma coagulation is first-line and radiofrequency ablation is second-line treatment for chronic bleeding secondary to gastric antral vascular ectasia. There are a variety of endoscopic treatment modalities for cirrhosis-related gastrointestinal bleeding, and the appropriate therapy depends on the location of the bleed, history or presence of acute bleeding, and risk factors for intervention-related adverse events.

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References
1.
Wahab P, Mulder C, den Hartog G, Thies J . Argon plasma coagulation in flexible gastrointestinal endoscopy: pilot experiences. Endoscopy. 1997; 29(3):176-81. DOI: 10.1055/s-2007-1004159. View

2.
Chiu Y, Lu L, Wu K, Tam W, Hu M, Tai W . Comparison of argon plasma coagulation in management of upper gastrointestinal angiodysplasia and gastric antral vascular ectasia hemorrhage. BMC Gastroenterol. 2012; 12:67. PMC: 3439282. DOI: 10.1186/1471-230X-12-67. View

3.
Yusoff I, Brennan F, Ormonde D, Laurence B . Argon plasma coagulation for treatment of watermelon stomach. Endoscopy. 2002; 34(5):407-10. DOI: 10.1055/s-2002-25287. View

4.
Carbonell N, Pauwels A, Serfaty L, Fourdan O, Levy V, Poupon R . Improved survival after variceal bleeding in patients with cirrhosis over the past two decades. Hepatology. 2004; 40(3):652-9. DOI: 10.1002/hep.20339. View

5.
Liou I . Management of end-stage liver disease. Med Clin North Am. 2013; 98(1):119-52. DOI: 10.1016/j.mcna.2013.09.006. View