The Association of Latent Toxoplasmosis and Level of Serum Testosterone in Humans

Overview

Journal BMC Res Notes

Publisher Biomed Central

Specialties Biology
General Medicine

Date 2018 Jun 10

PMID 29884208

Citations 9

Authors

Nima Zouei

Saeedeh Shojaee

Mehdi Mohebali

Hossein Keshavarz

Affiliations

Soon will be listed here.

Abstract

Objectives: Latent toxoplasmosis modifies various hormones and behaviors in infected hosts and possibly involves in etiology of different neurologic and psychiatric disorders. The aim of the current study was to assess possible associations between latent toxoplasmosis and testosterone concentration in Toxoplasma infected and free subjects. Briefly, 18-49 year-old participated in the study. After collected blood samples, sera were analyzed for the detection of anti-Toxoplasma IgG antibody. Totally, 76 positive sera were selected as study group (38 from men and 38 from women) and a same number of negative sera as control group.

Results: Comparison of testosterone concentrations and control groups showed that testosterone concentration in study group was higher than that in control group with statistically significant difference (P = 0.024 and P = 0.043 for men and women, respectively). Significant differences were found in testosterone concentrations and anti-Toxoplasma IgG antibody levels in study and control groups (P < 0.05). Toxoplasmosis can affect the mean concentration of serum testosterone in human. Alteration of testosterone during latent toxoplasmosis can result in alterations in behavioral, physiologic and immunological parameters in long time.

Citing Articles

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Toxoplasma gondii infection and testosterone alteration: A systematic review and meta-analyses.

Abdoli A, Ghaffarifar F, Sharifi Z, Taghipour A PLoS One. 2024; 19(4):e0297362.

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