Extended-spectrum Beta-lactamase-producing Escherichia Coli Meningitis That Developed from Otitis Media with Cholesteatoma

Overview

Journal Intern Med

Specialty General Medicine

Date 2018 Jun 8

PMID 29877280

Citations 3

Authors

Motofumi Tosa

Masako Aihara

Junko Murakami

Affiliations

Soon will be listed here.

Abstract

A 78-year-old man had a fever and exhibited disordered consciousness, which led to his transportation to our hospital. On arrival, he exhibited discharge from the ear. Because extended-spectrum beta-lactamase (ESBL)-producing Escherichia coli was detected in the ear discharge and cerebrospinal fluid specimens, it was inferred to be the causal bacteria. Pulsed-field gel electrophoresis indicated the same ESBL-producing E. coli pattern in the patient's ear discharge, external auditory canal granulation, cerebrospinal fluid, and stool, indicating their common molecular epidemiological origin. Although ESBL-producing E. coli is an extremely rare cause of bacterial meningitis, it should be considered as a potential causal bacteria for community-acquired meningitis.

Citing Articles

Meningitis Relapse in a Neonate: From Extended-Spectrum Beta-Lactamases-Producing Escherichia coli to Escherichia coli K1.

Alkattan S, AlTurki S, Khan B Cureus. 2022; 14(11):e31601.

PMID: 36540472 PMC: 9758959. DOI: 10.7759/cureus.31601.

Septic shock due to Escherichia coli meningoencephalitis treated with immunoglobulin-M-enriched immunoglobulin preparation as adjuvant therapy: a case report.

Pota V, Passavanti M, Coppolino F, Di Zazzo F, De Nardis L, Esposito R J Med Case Rep. 2021; 15(1):138.

PMID: 33775244 PMC: 8005330. DOI: 10.1186/s13256-021-02731-7.

Phenotype, molecular characterisation and risk factors for postoperative meningitis caused by ESBL-producing-Enterobacteriaceae: a six years multi-Centre comparative cohort study.

Zheng G, Cao Y, Liu C, Qian L, Cai Y, Cui M BMC Infect Dis. 2021; 21(1):85.

PMID: 33468073 PMC: 7816392. DOI: 10.1186/s12879-021-05784-7.

References

Knothe H, Shah P, Krcmery V, Antal M, Mitsuhashi S . Transferable resistance to cefotaxime, cefoxitin, cefamandole and cefuroxime in clinical isolates of Klebsiella pneumoniae and Serratia marcescens. Infection. 1983; 11(6):315-7. DOI: 10.1007/BF01641355. View

Gon Y, Otsubo R, Murase S, Park K, Nakazawa K, Hara H . [Case of an elderly patient with community acquired bacterial meningitis due to extended spectrum β lactamase producing Escherichia coli]. Rinsho Shinkeigaku. 2012; 52(1):12-8. DOI: 10.5692/clinicalneurol.52.12. View

Boyer-Mariotte S, Duboc P, Bonacorsi S, Lemeland J, Bingen E, Pinquier D . CTX-M-15-producing Escherichia coli in fatal neonatal meningitis: failure of empirical chemotherapy. J Antimicrob Chemother. 2008; 62(6):1472-4. DOI: 10.1093/jac/dkn362. View

Yumuk Z, Afacan G, Nicolas-Chanoine M, Sotto A, Lavigne J . Turkey: a further country concerned by community-acquired Escherichia coli clone O25-ST131 producing CTX-M-15. J Antimicrob Chemother. 2008; 62(2):284-8. DOI: 10.1093/jac/dkn181. View

Andrade L, Minarini L, Pitondo-Silva A, Climaco E, Palazzo I, Medeiros M . Determinants of beta-lactam resistance in meningitis-causing Enterobacteriaceae in Brazil. Can J Microbiol. 2010; 56(5):399-407. DOI: 10.1139/w10-020. View

Colodner R, Rock W, Chazan B, Keller N, Guy N, Sakran W . Risk factors for the development of extended-spectrum beta-lactamase-producing bacteria in nonhospitalized patients. Eur J Clin Microbiol Infect Dis. 2004; 23(3):163-7. DOI: 10.1007/s10096-003-1084-2. View

Skaf G, Domloj N, Fehlings M, Bouclaous C, Sabbagh A, Kanafani Z . Pyogenic spondylodiscitis: an overview. J Infect Public Health. 2010; 3(1):5-16. DOI: 10.1016/j.jiph.2010.01.001. View

Rodriguez-Bano J, Alcala J, Cisneros J, Grill F, Oliver A, Horcajada J . Community infections caused by extended-spectrum beta-lactamase-producing Escherichia coli. Arch Intern Med. 2008; 168(17):1897-902. DOI: 10.1001/archinte.168.17.1897. View

Pitout J, Hanson N, Church D, Laupland K . Population-based laboratory surveillance for Escherichia coli-producing extended-spectrum beta-lactamases: importance of community isolates with blaCTX-M genes. Clin Infect Dis. 2004; 38(12):1736-41. DOI: 10.1086/421094. View

10.

Moissenet D, Salauze B, Clermont O, Bingen E, Arlet G, Denamur E . Meningitis caused by Escherichia coli producing TEM-52 extended-spectrum beta-lactamase within an extensive outbreak in a neonatal ward: epidemiological investigation and characterization of the strain. J Clin Microbiol. 2010; 48(7):2459-63. PMC: 2897521. DOI: 10.1128/JCM.00529-10. View

11.

Elaldi N, Gozel M, Kolayli F, Engin A, Celik C, Bakici M . Community-acquired CTX-M-15-type ESBL-producing Escherichia coli meningitis: a case report and literature review. J Infect Dev Ctries. 2013; 7(5):424-31. DOI: 10.3855/jidc.2820. View

12.

Kader A, Kumar A, Kamath K . Fecal carriage of extended-spectrum beta-lactamase-producing Escherichia coli and Klebsiella pneumoniae in patients and asymptomatic healthy individuals. Infect Control Hosp Epidemiol. 2007; 28(9):1114-6. DOI: 10.1086/519865. View

13.

Chaiyakulsil C, Prommalikit O . Successful medical treatment in a child with E. coli ESBL meningitis with acute communicating hydrocephalus and ventricular empyema: a case report. J Med Assoc Thai. 2013; 95 Suppl 12:S138-41. View

14.

Tunkel A, Hartman B, Kaplan S, Kaufman B, Roos K, Scheld W . Practice guidelines for the management of bacterial meningitis. Clin Infect Dis. 2004; 39(9):1267-84. DOI: 10.1086/425368. View

15.

Dellinger R, Carlet J, Masur H, Gerlach H, Calandra T, Cohen J . Surviving Sepsis Campaign guidelines for management of severe sepsis and septic shock. Crit Care Med. 2004; 32(3):858-73. DOI: 10.1097/01.ccm.0000117317.18092.e4. View

16.

Nakwan N, Nakwan N, Wannaro J, Dissaneevate P, Kritsaneepaiboon S, Chokephaibulkit K . Septicemia, meningitis, and skull osteomyelitis complicating infected cephalhematoma caused by ESBL-producing Escherichia coli. Southeast Asian J Trop Med Public Health. 2011; 42(1):148-51. View

17.

Kliebe C, NIES B, Meyer J, Wiedemann B . Evolution of plasmid-coded resistance to broad-spectrum cephalosporins. Antimicrob Agents Chemother. 1985; 28(2):302-7. PMC: 180236. DOI: 10.1128/AAC.28.2.302. View

18.

Ben-Ami R, Rodriguez-Bano J, Arslan H, Pitout J, Quentin C, Calbo E . A multinational survey of risk factors for infection with extended-spectrum beta-lactamase-producing enterobacteriaceae in nonhospitalized patients. Clin Infect Dis. 2009; 49(5):682-90. DOI: 10.1086/604713. View

19.

Weyrich P, Ettahar N, Legout L, Meybeck A, Leroy O, Senneville E . First initial community-acquired meningitis due to extended-spectrum beta-lactamase producing Escherichia coli complicated with multiple aortic mycotic aneurysms. Ann Clin Microbiol Antimicrob. 2012; 11:4. PMC: 3297508. DOI: 10.1186/1476-0711-11-4. View

20.

Bradford P . Extended-spectrum beta-lactamases in the 21st century: characterization, epidemiology, and detection of this important resistance threat. Clin Microbiol Rev. 2001; 14(4):933-51, table of contents. PMC: 89009. DOI: 10.1128/CMR.14.4.933-951.2001. View