Spotlight On… Gabriella Campadelli-Fiume

Overview

Journal FEMS Microbiol Lett

Publisher Oxford University Press

Specialty Microbiology

Date 2018 Jun 7

PMID 29873707

Authors

Gabriella Campadelli-Fiume

Affiliations

Soon will be listed here.

References

Gianni T, Gatta V, Campadelli-Fiume G . {alpha}V{beta}3-integrin routes herpes simplex virus to an entry pathway dependent on cholesterol-rich lipid rafts and dynamin2. Proc Natl Acad Sci U S A. 2010; 107(51):22260-5. PMC: 3009828. DOI: 10.1073/pnas.1014923108. View

Gianni T, Campadelli-Fiume G . The epithelial αvβ3-integrin boosts the MYD88-dependent TLR2 signaling in response to viral and bacterial components. PLoS Pathog. 2014; 10(11):e1004477. PMC: 4223072. DOI: 10.1371/journal.ppat.1004477. View

Campadelli-Fiume G, De Giovanni C, Gatta V, Nanni P, Lollini P, Menotti L . Rethinking herpes simplex virus: the way to oncolytic agents. Rev Med Virol. 2011; 21(4):213-26. DOI: 10.1002/rmv.691. View

Campadelli-Fiume G, Amasio M, Avitabile E, Cerretani A, Forghieri C, Gianni T . The multipartite system that mediates entry of herpes simplex virus into the cell. Rev Med Virol. 2007; 17(5):313-26. DOI: 10.1002/rmv.546. View

Fusco D, Forghieri C, Campadelli-Fiume G . The pro-fusion domain of herpes simplex virus glycoprotein D (gD) interacts with the gD N terminus and is displaced by soluble forms of viral receptors. Proc Natl Acad Sci U S A. 2005; 102(26):9323-8. PMC: 1166633. DOI: 10.1073/pnas.0503907102. View

Brandimarti R, Huang T, Roizman B . Mapping of herpes simplex virus 1 genes with mutations which overcome host restrictions to infection. Proc Natl Acad Sci U S A. 1994; 91(12):5406-10. PMC: 44004. DOI: 10.1073/pnas.91.12.5406. View

Cocchi F, Fusco D, Menotti L, Gianni T, Eisenberg R, Cohen G . The soluble ectodomain of herpes simplex virus gD contains a membrane-proximal pro-fusion domain and suffices to mediate virus entry. Proc Natl Acad Sci U S A. 2004; 101(19):7445-50. PMC: 409938. DOI: 10.1073/pnas.0401883101. View

Cocchi F, Menotti L, Lopez M . The novel receptors that mediate the entry of herpes simplex viruses and animal alphaherpesviruses into cells. Rev Med Virol. 2000; 10(5):305-19. DOI: 10.1002/1099-1654(200009/10)10:5<305::aid-rmv286>3.0.co;2-t. View

Menotti L, Lopez M, Avitabile E, Stefan A, Cocchi F, Adelaide J . The murine homolog of human Nectin1delta serves as a species nonspecific mediator for entry of human and animal alpha herpesviruses in a pathway independent of a detectable binding to gD. Proc Natl Acad Sci U S A. 2000; 97(9):4867-72. PMC: 18324. DOI: 10.1073/pnas.97.9.4867. View

10.

Cocchi F, Lopez M, Menotti L, Aoubala M, Dubreuil P . The V domain of herpesvirus Ig-like receptor (HIgR) contains a major functional region in herpes simplex virus-1 entry into cells and interacts physically with the viral glycoprotein D. Proc Natl Acad Sci U S A. 1998; 95(26):15700-5. PMC: 28107. DOI: 10.1073/pnas.95.26.15700. View

11.

Nanni P, Gatta V, Menotti L, De Giovanni C, Ianzano M, Palladini A . Preclinical therapy of disseminated HER-2⁺ ovarian and breast carcinomas with a HER-2-retargeted oncolytic herpesvirus. PLoS Pathog. 2013; 9(1):e1003155. PMC: 3561254. DOI: 10.1371/journal.ppat.1003155. View

12.

Menotti L, Nicoletti G, Gatta V, Croci S, Landuzzi L, De Giovanni C . Inhibition of human tumor growth in mice by an oncolytic herpes simplex virus designed to target solely HER-2-positive cells. Proc Natl Acad Sci U S A. 2009; 106(22):9039-44. PMC: 2684841. DOI: 10.1073/pnas.0812268106. View

13.

Gianni T, Leoni V, Chesnokova L, Hutt-Fletcher L, Campadelli-Fiume G . αvβ3-integrin is a major sensor and activator of innate immunity to herpes simplex virus-1. Proc Natl Acad Sci U S A. 2012; 109(48):19792-7. PMC: 3511702. DOI: 10.1073/pnas.1212597109. View

14.

Cocchi F, Menotti L, Mirandola P, Lopez M . The ectodomain of a novel member of the immunoglobulin subfamily related to the poliovirus receptor has the attributes of a bona fide receptor for herpes simplex virus types 1 and 2 in human cells. J Virol. 1998; 72(12):9992-10002. PMC: 110516. DOI: 10.1128/JVI.72.12.9992-10002.1998. View

15.

Gianni T, Massaro R, Campadelli-Fiume G . Dissociation of HSV gL from gH by αvβ6- or αvβ8-integrin promotes gH activation and virus entry. Proc Natl Acad Sci U S A. 2015; 112(29):E3901-10. PMC: 4517248. DOI: 10.1073/pnas.1506846112. View

16.

Menotti L, Cerretani A, Hengel H, Campadelli-Fiume G . Construction of a fully retargeted herpes simplex virus 1 recombinant capable of entering cells solely via human epidermal growth factor receptor 2. J Virol. 2008; 82(20):10153-61. PMC: 2566291. DOI: 10.1128/JVI.01133-08. View

17.

Qi S, Avitabile E, Brandimarti R, Roizman B . Glycoprotein D of herpes simplex virus encodes a domain which precludes penetration of cells expressing the glycoprotein by superinfecting herpes simplex virus. J Virol. 1990; 64(12):6070-9. PMC: 248781. DOI: 10.1128/JVI.64.12.6070-6079.1990. View