» Articles » PMID: 29872246

Intervention in Massive Pulmonary Embolus: Catheter Thrombectomy/Thromboaspiration Versus Systemic Lysis Versus Surgical Thrombectomy

Overview
Specialty Radiology
Date 2018 Jun 7
PMID 29872246
Citations 4
Authors
Affiliations
Soon will be listed here.
Abstract

Massive pulmonary embolus (PE), defined as hemodynamic shock from acute PE, is a life-threatening condition. Deaths from massive PE, especially when unsuspected, occur within minutes to hours of onset and as such prompt intervention can be lifesaving. Acute massive PE patients have traditionally been candidates for treatment with intravenous systemic thrombolysis to improve pulmonary artery pressure, arteriovenous oxygenation, and pulmonary perfusion in an effort to reduce mortality. However, patients with contraindications to systemic thrombolysis or those who have failed thrombolysis may benefit from other techniques including endovascular and surgical embolectomy. This article will review the current medical management as well as catheter-directed therapies and surgical embolectomy in the treatment of patients with massive PE.

Citing Articles

Catheter-directed therapy to treat intermediateand high-risk pulmonary embolism: Personal experience and review of the literature.

Pietrasik A, Gasecka A, Kotulecki A, Karolak P, Araszkiewicz A, Darocha S Cardiol J. 2022; 30(3):462-472.

PMID: 35975795 PMC: 10287075. DOI: 10.5603/CJ.a2022.0075.


Catheter-Based Therapies Decrease Mortality in Patients With Intermediate and High-Risk Pulmonary Embolism: Evidence From Meta-Analysis of 65,589 Patients.

Pietrasik A, Gasecka A, Szarpak L, Pruc M, Kopiec T, Darocha S Front Cardiovasc Med. 2022; 9:861307.

PMID: 35783825 PMC: 9243366. DOI: 10.3389/fcvm.2022.861307.


Emergent mechanical thrombectomy for right atrial clot and massive pulmonary embolism using flowtriever.

Bayona Molano M, Salsamendi J, Mani N Clin Case Rep. 2021; 9(3):1241-1246.

PMID: 33768819 PMC: 7981718. DOI: 10.1002/ccr3.3739.


Role of Interventional Radiologist in the Management of Acute Pulmonary Embolism.

Bremer W, Ray Jr C, Shah K Semin Intervent Radiol. 2020; 37(1):62-73.

PMID: 32139972 PMC: 7056338. DOI: 10.1055/s-0039-3401841.

References
1.
Piazza G, Hohlfelder B, Jaff M, Ouriel K, Engelhardt T, Sterling K . A Prospective, Single-Arm, Multicenter Trial of Ultrasound-Facilitated, Catheter-Directed, Low-Dose Fibrinolysis for Acute Massive and Submassive Pulmonary Embolism: The SEATTLE II Study. JACC Cardiovasc Interv. 2015; 8(10):1382-1392. DOI: 10.1016/j.jcin.2015.04.020. View

2.
Torbicki A, Perrier A, Konstantinides S, Agnelli G, Galie N, Pruszczyk P . Guidelines on the diagnosis and management of acute pulmonary embolism: the Task Force for the Diagnosis and Management of Acute Pulmonary Embolism of the European Society of Cardiology (ESC). Eur Heart J. 2008; 29(18):2276-315. DOI: 10.1093/eurheartj/ehn310. View

3.
White R . The epidemiology of venous thromboembolism. Circulation. 2003; 107(23 Suppl 1):I4-8. DOI: 10.1161/01.CIR.0000078468.11849.66. View

4.
French K, White J, Hoesch R . Treatment of intracerebral hemorrhage with tranexamic acid after thrombolysis with tissue plasminogen activator. Neurocrit Care. 2012; 17(1):107-11. DOI: 10.1007/s12028-012-9681-5. View

5.
Huisman M, Buller H, Ten Cate J, van Royen E, Vreeken J, Kersten M . Unexpected high prevalence of silent pulmonary embolism in patients with deep venous thrombosis. Chest. 1989; 95(3):498-502. DOI: 10.1378/chest.95.3.498. View