Sustained Sexual Behavior Change After Acute HIV Diagnosis in Malawi

Overview

Journal Sex Transm Dis

Specialty Infectious Diseases

Date 2018 Jun 6

PMID 29870501

Citations 6

Authors

Katherine B Rucinski

Sarah E Rutstein

Kimberly A Powers

Dana K Pasquale

Ann M Dennis

Sam Phiri

Mina C Hosseinipour

Gift Kamanga

Dominic Nsona

Cecilia Massa

Irving F Hoffman

William C Miller

Audrey E Pettifor

Affiliations

Soon will be listed here.

Abstract

Background: Identification of acute HIV infection (AHI) allows for important opportunities for HIV prevention through behavior change and biomedical intervention. Here, we evaluate changes in sexual risk behaviors among persons with AHI enrolled in a combined behavioral and biomedical intervention designed to reduce onward transmission of HIV.

Methods: Participants were randomized to standard HIV counseling, a multisession behavioral intervention, or a multisession behavioral intervention plus antiretrovirals. Sexual behaviors were assessed periodically over 1 year.

Results: Four weeks after diagnosis, the predicted probability of reporting multiple sexual partners decreased from 24% to 9%, and the probability of reporting unprotected sex decreased from 71% to 27%. These declines in sexual risk behaviors were sustained over follow-up irrespective of study arm.

Conclusions: Diagnosis of AHI alone may be sufficient to achieve immediate and sustained behavior change during this highly infectious period.

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