Risk Factors for Early-onset Ventilator-associated Pneumonia in Aneurysmal Subarachnoid Hemorrhage Patients

Overview

Journal Braz J Med Biol Res

Specialties Biology
General Medicine

Date 2018 May 24

PMID 29791584

Citations 7

Authors

J B Cui

Q Q Chen

T T Liu

S J Li

Affiliations

Soon will be listed here.

Abstract

This study aimed to investigate the risk factors related to ventilator-acquired pneumonia (VAP) in aneurysmal subarachnoid hemorrhage (SAH) patients. From January 2011 to December 2015, a single-center retrospective study including 200 SAH patients requiring mechanical ventilation (MV) ≥48 h was performed. The clinical data of these patients were collected and analyzed. The age range of the patients were 41-63 and 72 (36%) were male. The Glasgow coma scale score range was 5-15 and the Simplified Acute Physiology Score II range was 31-52. One hundred and forty-eight (74%) patients had a World Federation of Neurosurgeons (WNFS) score ≥III. Aneurysm was secured with an endovascular coiling procedure in 168 (84%) patients and 94 (47%) patients presented VAP. Male gender (OR=2.25, 95%CI=1.15-4.45), use of mannitol (OR=3.02, 95%CI=1.53-5.94) and enteral feeding above 20 kcal·kg-1·day-1 (OR=2.90, 95%CI=1.26-6.67) after day 7 were independent factors for VAP. Patients with early-onset VAP had a longer duration of sedation (P=0.03), MV (P=0.001) and ICU length of stay (P=0.003) and a worse Glasgow Outcome Scale score (P<0.001), but did not have a higher death rate.

Citing Articles

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Neutrophil-lymphocyte ratio on first and third postoperative days: associated with severe pneumonia in aneurysmal subarachnoid hemorrhage patients undergoing surgeries.

Wang X, Zhao Y, Zhao J, Deng L Neurosurg Rev. 2024; 47(1):70.

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Wu M, Chen Y, Li Z, Gu H, Yang K, Xiong Y CNS Neurosci Ther. 2022; 28(6):913-921.

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Scislo L, Walewska E, Bodys-Cupak I, Gniadek A, Kozka M Int J Environ Res Public Health. 2022; 19(1).

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