» Articles » PMID: 29789123

Amputation Stump Perfusion is Predictive of Post-operative Necrotic Eschar Formation

Overview
Journal Am J Surg
Specialty General Surgery
Date 2018 May 24
PMID 29789123
Citations 1
Authors
Affiliations
Soon will be listed here.
Abstract

Background: A large proportion of patients develop poor amputation stump healing. We hypothesize that Laser-Assisted Fluorescent Angiography (LAFA) can predict inadequate tissue perfusion and healing.

Methods: Over an 8-month period we reviewed all patients who underwent lower extremity amputation and LAFA. We evaluated intra-operative LAFA global and segmental stump perfusion, and post-operative modified Bates-Jensen (mBJS) wound healing scores.

Results: In 15 patients, amputation stumps with lower global perfusion demonstrated higher mBJS (P = 0.01). Lower suture-line perfusion also correlated with more eschar formation (P < 0.001). Diabetic patients had higher mBJS (P = 0.009), lower stump perfusion (P = 0.02), and increased eschar volume (P < 0.001).

Conclusion: LAFA is a useful adjunct for intra-operative stump perfusion assessment and can predict areas of poor stump healing and eschar formation. Diabetic patients seem to be at higher risk of stump eschar formation.

Citing Articles

Wound management, healing, and early prosthetic rehabilitation: Part 1 - A scoping review of healing and non-healing definitions.

Williams-Reid H, Johannesson A, Buis A Can Prosthet Orthot J. 2025; 7(2):43715.

PMID: 39990241 PMC: 11844765. DOI: 10.33137/cpoj.v7i2.43715.


Detection of wound healing disorders after major amputations by measurements of the microcirculation: A prospective single-center study.

Zetzmann K, Papatheodorou N, Ruhl E, Yagshyyev S, Haney B, Moosmann O SAGE Open Med. 2024; 12:20503121241263244.

PMID: 39055279 PMC: 11271087. DOI: 10.1177/20503121241263244.

References
1.
Wang Z, Hasan R, Firwana B, Elraiyah T, Tsapas A, Prokop L . A systematic review and meta-analysis of tests to predict wound healing in diabetic foot. J Vasc Surg. 2016; 63(2 Suppl):29S-36S.e1-2. DOI: 10.1016/j.jvs.2015.10.004. View

2.
WAGNER W, Keagy B, Kotb M, Burnham S, JOHNSON Jr G . Noninvasive determination of healing of major lower extremity amputation: the continued role of clinical judgment. J Vasc Surg. 1988; 8(6):703-10. View

3.
Hasanadka R, McLafferty R, Moore C, Hood D, Ramsey D, Hodgson K . Predictors of wound complications following major amputation for critical limb ischemia. J Vasc Surg. 2011; 54(5):1374-82. DOI: 10.1016/j.jvs.2011.04.048. View

4.
EBSKOV B, Josephsen P . Incidence of reamputation and death after gangrene of the lower extremity. Prosthet Orthot Int. 1980; 4(2):77-80. DOI: 10.3109/03093648009164567. View

5.
Keyzer-Dekker C, Moerman E, Leijdekkers V, Vahl A . Can transcutaneous oxygen tension measurement determine re-amputation levels?. J Wound Care. 2006; 15(1):27-30. DOI: 10.12968/jowc.2006.15.1.26860. View