Seroprevalence of Cystic Echinococcosis in Blood Donors in Fars Province, Southern Iran

Overview

Journal Parasite Epidemiol Control

Specialty Parasitology

Date 2018 May 19

PMID 29774277

Citations 14

Authors

Bahador Sarkari

Farshid Hosseini

Samaneh Abdolahi Khabisi

Farzaneh Sedaghat

Affiliations

Soon will be listed here.

Abstract

Cystic echinococcosis (CE) is one of the most important zoonotic diseases in different geographical areas of the world including Iran. The current study aimed to assess the seroprevalence of human cystic echinococcosis (CE) in healthy blood donors in Fars province, southern Iran. A total of 1068 serum samples were collected from blood donors from five blood service centers of Fars province in south of Iran. Antigen B was prepared from sheep hydatid cyst fluid and collected sera were evaluated for anti-hydatid cyst antibodies, using antigen-B ELISA. Demographic features of the participants were also recorded during the sample collection. Anti hydatid cyst antibodies were detected in sera of 60 out of 1068 blood donors corresponding to overall seroprevalence of 5.6% in this population. Rate of seroprevalence was 6.7% in females and 5.5% in males. The highest rate of infection (8.3%) was found in age group of higher than 50 years old. There were no significant differences between seropositivity to CE and sex, age or place of residence of the participants (P > 0.05). Findings of this study showed that the rate of CE infection in Fars province, southern Iran, is relatively high. Some of these seropositive cases may have active hydatid cyst in their tissues without overt sign or symptoms.

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References

Sadjjadi S, Sedaghat F, Hosseini S, Sarkari B . Serum antigen and antibody detection in echinococcosis: application in serodiagnosis of human hydatidosis. Korean J Parasitol. 2009; 47(2):153-7. PMC: 2688797. DOI: 10.3347/kjp.2009.47.2.153. View

Yang Y, Craig P, Vuitton D, Williams G, Sun T, Liu T . Serological prevalence of echinococcosis and risk factors for infection among children in rural communities of southern Ningxia, China. Trop Med Int Health. 2008; 13(8):1086-94. DOI: 10.1111/j.1365-3156.2008.02101.x. View

Zibaei M, Azargoon A, Ataie-Khorasgani M, Ghanadi K, Sadjjadi S . The serological study of cystic echinococcosis and assessment of surgical cases during 5 years (2007-2011) in Khorram Abad, Iran. Niger J Clin Pract. 2013; 16(2):221-5. DOI: 10.4103/1119-3077.110156. View

Sarkari B, Gadami F, Shafiei R, Motazedian M, Sedaghat F, Kasraian L . Seroprevalence of Leishmania infection among the healthy blood donors in kala-azar endemic areas of Iran. J Parasit Dis. 2015; 39(3):545-9. PMC: 4554570. DOI: 10.1007/s12639-013-0393-3. View

Ziaei H, Fakhar M, Armat S . Epidemiological aspects of cystic echinococcosis in slaughtered herbivores in Sari abattoir, North of Iran. J Parasit Dis. 2012; 35(2):215-8. PMC: 3235372. DOI: 10.1007/s12639-011-0051-6. View

Eckert J, Deplazes P . Biological, epidemiological, and clinical aspects of echinococcosis, a zoonosis of increasing concern. Clin Microbiol Rev. 2004; 17(1):107-35. PMC: 321468. DOI: 10.1128/CMR.17.1.107-135.2004. View

Qaqish A, Nasrieh M, Al-Qaoud K, Craig P, Abdel-Hafez S . The seroprevalences of cystic echinococcosis, and the associated risk factors, in rural-agricultural, bedouin and semi-bedouin communities in Jordan. Ann Trop Med Parasitol. 2003; 97(5):511-20. DOI: 10.1179/000349803225001436. View

Mohammadzadeh T, Sako Y, Sadjjadi S, Sarkari B, Ito A . Comparison of the usefulness of hydatid cyst fluid, native antigen B and recombinant antigen B8/1 for serological diagnosis of cystic echinococcosis. Trans R Soc Trop Med Hyg. 2012; 106(6):371-5. DOI: 10.1016/j.trstmh.2012.01.012. View

Ahmadi N, Badi F . Human hydatidosis in Tehran, Iran: a retrospective epidemiological study of surgical cases between 1999 and 2009 at two university medical centers. Trop Biomed. 2011; 28(2):450-6. View

10.

Heidari Z, Mohebali M, Zarei Z, Aryayipour M, Eshraghian M, Kia E . Seroepidemiological study of human hydatidosis in meshkinshahr district, ardabil province, iran. Iran J Parasitol. 2012; 6(3):19-25. PMC: 3279891. View

11.

Sarkari B, Rezaei Z . Immunodiagnosis of human hydatid disease: Where do we stand?. World J Methodol. 2015; 5(4):185-95. PMC: 4686415. DOI: 10.5662/wjm.v5.i4.185. View

12.

Asghari M, Mohebali M, Kia E, Farahnak A, Aryaeipour M, Asadian S . Seroepidemiology of Human Hydatidosis Using AgB-ELISA Test in Arak, Central Iran. Iran J Public Health. 2013; 42(4):391-6. PMC: 3684725. View

13.

Harandi M, Budke C, Rostami S . The monetary burden of cystic echinococcosis in Iran. PLoS Negl Trop Dis. 2012; 6(11):e1915. PMC: 3510083. DOI: 10.1371/journal.pntd.0001915. View

14.

Dalimi A, Motamedi G, Hosseini M, Mohammadian B, Malaki H, Ghamari Z . Echinococcosis/hydatidosis in western Iran. Vet Parasitol. 2002; 105(2):161-71. DOI: 10.1016/s0304-4017(02)00005-5. View

15.

Sadjjadi S, Abidi H, Sarkari B, Izadpanah A, Kazemian S . Evaluation of enzyme linked immunosorbent assay, utilizing native antigen B for serodiagnosis of human hydatidosis. Iran J Immunol. 2007; 4(3):167-72. DOI: IJIv4i3A5. View

16.

Elham M, Hassan B, Ghasem N, Gholamreza R, Parviz S . Epidemiological study of hydatidosis in the dromedaries (Camelus dromedarius) of different regions of Iran. Asian Pac J Trop Biomed. 2014; 4(Suppl 1):S148-51. PMC: 4025301. DOI: 10.12980/APJTB.4.2014C725. View

17.

Sarkari B, Shafiei R, Zare M, Sohrabpour S, Kasraian L . Seroprevalence and molecular diagnosis of Toxoplasma gondii infection among blood donors in southern Iran. J Infect Dev Ctries. 2014; 8(4):543-7. DOI: 10.3855/jidc.3831. View

18.

Abu-Hasan N, Daragmeh M, Adwan K, Al-Qaoud K, Abdel-Hafez S . Human cystic echinococcosis in the West Bank of Palestine: surgical incidence and seroepidemiological study. Parasitol Res. 2002; 88(2):107-12. DOI: 10.1007/s004360100426. View

19.

Cetinkaya Z, Ciftci I, Demirel R, Altindis M, Ayaz E . A sero-epidemiologic study on cystic echinococcosis in midwestern region of Turkey. Saudi Med J. 2005; 26(2):350-1. View

20.

Sarkari B, Sadjjadi S, Beheshtian M, Aghaee M, Sedaghat F . Human cystic echinococcosis in Yasuj District in Southwest of Iran: an epidemiological study of seroprevalence and surgical cases over a ten-year period. Zoonoses Public Health. 2009; 57(2):146-50. DOI: 10.1111/j.1863-2378.2008.01200.x. View