A Review: The Bioactivities and Pharmacological Applications of Polygonatum Sibiricum Polysaccharides

Overview

Journal Molecules

Publisher MDPI

Specialty Biology

Date 2018 May 15

PMID 29757991

Citations 68

Authors

Xiaowei Cui

Shiyuan Wang

Hui Cao

Hong Guo

Yujuan Li

Fangxue Xu

Mengmeng Zheng

Xiaozhi Xi

Chunchao Han

Affiliations

Soon will be listed here.

Abstract

Traditional Chinese Medicine (TCM) has been widely used in China and is regarded as the most important therapeutic. (PS), a natural plant used in traditional Chinese medicine, has various functions associated with a number of its components. There are many compositions in PS including polysaccharides, steroids, anthraquinone, alkaloids, cardiac glycosides, lignin, vitamins, various acids, and so on. Of these, polysaccharides play a significant role in PS-based therapeutics. This article summarizes polysaccharides (PSP) have many pharmacological applications and biological activities, such as their antioxidant activity, anti-aging activity, an anti-fatigue effect, immunity enhancement effect, antibacterial effect, anti-inflammatory effect, hypolipidemic and antiatherosclerotic effects, anti-osteoporosis effect, liver protection, treatment of diabetes mellitus (DM), anti-cancer effect, and may help prevent Alzheimer's disease, and so on. This review summarized the extraction method, purification method, compositions, pharmacological applications, biological activities, biosynthesis, and prospects of PSP, providing a basis for further study of PS and PSP.

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