Medicinal Plants Used in the Treatment of Human Immunodeficiency Virus

Overview

Journal Int J Mol Sci

Publisher MDPI

Specialties Biochemistry
Chemistry
Molecular Biology

Date 2018 May 15

PMID 29757986

Citations 41

Authors

Bahare Salehi

Nanjangud V Anil Kumar

Bilge Sener

Mehdi Sharifi-Rad

Mehtap Kilic

Gail B Mahady

Sanja Vlaisavljevic

Marcello Iriti

Farzad Kobarfard

William N Setzer

Seyed Abdulmajid Ayatollahi

Athar Ata

Javad Sharifi-Rad

Affiliations

Soon will be listed here.

Abstract

Since the beginning of the epidemic, human immunodeficiency virus (HIV) has infected around 70 million people worldwide, most of whom reside is sub-Saharan Africa. There have been very promising developments in the treatment of HIV with anti-retroviral drug cocktails. However, drug resistance to anti-HIV drugs is emerging, and many people infected with HIV have adverse reactions or do not have ready access to currently available HIV chemotherapies. Thus, there is a need to discover new anti-HIV agents to supplement our current arsenal of anti-HIV drugs and to provide therapeutic options for populations with limited resources or access to currently efficacious chemotherapies. Plant-derived natural products continue to serve as a reservoir for the discovery of new medicines, including anti-HIV agents. This review presents a survey of plants that have shown anti-HIV activity, both in vitro and in vivo.

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