Neutrophil-to-lymphocyte Ratio As a Prognostic Factor for Pharyngocutaneous Fistula After Total Laryngectomy

Overview

Journal Acta Otorhinolaryngol Ital

Specialty Otorhinolaryngology

Date 2018 May 15

PMID 29756613

Citations 8

Authors

F T Aires

R A Dedivitis

M A V Kulcsar

D M Ramos

C R Cernea

Affiliations

Soon will be listed here.

Abstract

The role of systemic inflammatory response as a prognostic factor has been proposed in a variety of cancers. The purpose of this study was to investigate the prognostic value of the pretreatment neutrophil-to-lymphocyte ratio (NLR) in the incidence of pharyngocutaneous fistula (PCF) in patients who underwent total laryngectomy. We conducted a retrospective cohort analysis of 141 patients with squamous cell carcinoma of larynx who underwent total laryngectomy from 2009 to 2015. The incidence of PCF was 49.6%. A higher risk of 23% was observed among patients with NLR > 2.5 for the occurrence of PCF (p = 0.007). Patients with laryngeal squamous cell carcinoma who present elevated values in the ration > LR> (> 2.5) presented a higher risk of developing pharyngocutaneous fistula in the postoperative setting of total laryngectomy.

Citing Articles

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Evaluation of the Incidence of Pharyngocutaneous Fistula after Total Laryngectomy.

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