Targeting Liver Cancer and Associated Pathologies in Mice with a Mitochondrial VDAC1-Based Peptide

Overview

Journal Neoplasia

Publisher Elsevier

Specialty Oncology

Date 2018 May 11

PMID 29747160

Citations 41

Authors

Srinivas Pittala

Yakov Krelin

Varda Shoshan-Barmatz

Affiliations

Soon will be listed here.

Abstract

Conclusion: These results show that the VDAC1-based peptide R-Tf-D-LP4 has multiple effects on liver cancer cells, leading to impairment of cell energy and metabolism homeostasis, induction of apoptosis, and elimination of liver cancer-associated processes, and thus represents a promising therapeutic approach for liver cancer.

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