Increase in Viability Due to the Accumulation of X Chromosome Mutations in Drosophila Melanogaster Males

Overview

Journal Genetica

Specialties Cell Biology
Genetics

Date 2018 May 11

PMID 29744733

Authors

Ronny C Woodruff

Michael A Balinski

Affiliations

Soon will be listed here.

Abstract

To increase our understanding of the role of new X-chromosome mutations in adaptive evolution, single-X Drosophila melanogaster males were mated with attached-X chromosome females, allowing the male X chromosome to accumulate mutations over 28 generations. Contrary to our hypothesis that male viability would decrease over time, due to the accumulation and expression of X-linked recessive deleterious mutations in hemizygous males, viability significantly increased. This increase may be attributed to germinal selection and to new X-linked beneficial or compensatory mutations, possibly supporting the faster-X hypothesis.

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