Recurrence of Pericarditis After Influenza Vaccination: a Case Report and Review of the Literature

Overview

Journal BMC Pharmacol Toxicol

Publisher Biomed Central

Specialty Pharmacology

Date 2018 May 6

PMID 29728118

Citations 16

Authors

Riccardo Mei

Emanuel Raschi

Elisabetta Poluzzi

Igor Diemberger

Fabrizio De Ponti

Affiliations

Soon will be listed here.

Abstract

Background: This case report describes a patient with pericarditis likely attributed to influenza vaccination (positive rechallenge), with a literature review.

Case Presentation: A 87-year old patient developed pericarditis after influenza vaccination, with acute chest pain, without ECG abnormalities or increased cardiac enzyme levels. Echocardiogram showed moderate pericardial effusion. Recovery was obtained through steroids One year later, few days after re-immunization, the patient experienced the same symptoms and was admitted to hospital with diagnosis of recurrence of pericarditis with severe pericardial effusion, again treated with steroids. Other possible causes were ruled out and the cardiologist recommended against influenza vaccinations in the future; the patient did not experience recurrence of pericarditis in the following 6 years. Cases of pericarditis following influenza immunization in the literature were also reviewed.

Conclusions: Pericarditis following immunization for influenza is very rarely reported in the literature. In a few cases, influenza vaccination seems likely responsible. We suggest considering recent immunization in patient's history as part of the differential diagnosis in elderly with chest pain.

Citing Articles

Unmasking the Enigma: Influenza Vaccine and the Rare Case of Post-Vaccination Pericarditis.

Yetiskul E, Agarwal A, Di Pietro G, Qaqish F, Khan S, Khan S Case Rep Infect Dis. 2024; 2024:2729208.

PMID: 38495477 PMC: 10944345. DOI: 10.1155/2024/2729208.

Influenza Type B Complicates a Previously Undiagnosed Case of Pericarditis.

Ivaturi K, Tsukhai V, Hassan W Cureus. 2022; 14(10):e30810.

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Acute Polyserositis with Cardiac Tamponade and Bilateral Refractory Pleural Effusion after ChAdOx1 nCoV-19 Vaccination.

Li G, Lee C, Huang C Vaccines (Basel). 2022; 10(8).

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Myopericarditis with hemorrhagic pericardial effusion following BNT162b2 mRNA COVID-19 vaccine.

S Generette G, Troyer J, Hemenway A, Al Zoubi M IDCases. 2022; 28:e01511.

PMID: 35646594 PMC: 9122740. DOI: 10.1016/j.idcr.2022.e01511.

Cardiac Adverse Events after Vaccination-A Systematic Review.

Parmar K, Subramanyam S, Del Rio-Pertuz G, Sethi P, Argueta-Sosa E Vaccines (Basel). 2022; 10(5).

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