In Vitro Selection of Electrochemical Peptide Probes Using Bioorthogonal TRNA for Influenza Virus Detection

Overview

Journal Chem Commun (Camb)

Publisher Royal Society of Chemistry

Specialty Chemistry

Date 2018 May 3

PMID 29718049

Citations 4

Authors

Tara Bahadur K C

Seiichi Tada

Liping Zhu

Takanori Uzawa

Noriko Minagawa

Shyh-Chyang Luo

Haichao Zhao

Hsiao-Hua Yu

Toshiro Aigaki

Yoshihiro Ito

Affiliations

Soon will be listed here.

Abstract

An electrosensitive peptide probe has been developed from an in vitro selection technique using biorthogonal tRNA prepared with an electroreactive non-natural amino acid, 3,4-ethylenedioxythiophene-conjugated aminophenylalanine. The selected probe quantitatively detected the influenza virus based on a signal "turn-on" mechanism. The developed strategy could be used to develop electrochemical biosensors toward a variety of targets.

Citing Articles

Chelation-Induced Zwitterion-like Antifouling Behavior on Anionic Poly(3,4-ethylenedioxythiophene) Surfaces.

Kao T, Gong Y, Huang C, Wu Y, Luo S Langmuir. 2024; 40(42):22417-22423.

PMID: 39383339 PMC: 11500425. DOI: 10.1021/acs.langmuir.4c03275.

Advancements in electrochemical biosensing for respiratory virus detection: A review.

Zhao Z, Huang C, Huang Z, Lin F, He Q, Tao D Trends Analyt Chem. 2021; 139:116253.

PMID: 33727755 PMC: 7952277. DOI: 10.1016/j.trac.2021.116253.

Expanding the Chemical Diversity of Genetically Encoded Libraries.

Iskandar S, Haberman V, Bowers A ACS Comb Sci. 2020; 22(12):712-733.

PMID: 33167616 PMC: 8284915. DOI: 10.1021/acscombsci.0c00179.

Detecting and Predicting Emerging Disease in Poultry With the Implementation of New Technologies and Big Data: A Focus on Avian Influenza Virus.

Astill J, Dara R, Fraser E, Sharif S Front Vet Sci. 2018; 5:263.

PMID: 30425995 PMC: 6218608. DOI: 10.3389/fvets.2018.00263.