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Mortality in Advanced Chronic Obstructive Pulmonary Disease and Heart Failure Following Cardiopulmonary Rehabilitation

Overview
Journal Biol Res Nurs
Specialties Biology
Nursing
Date 2018 May 1
PMID 29706089
Citations 3
Authors
Affiliations
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Abstract

Methods And Results: In this secondary analysis of a randomized controlled trial comparing two CR methods in severe COPD and HF, 90 (COPD = 63, HF = 27) male veterans, mean age 66 ± 9.24 years, 79% Caucasian, and body mass index 31 kg/m, were followed for 12 months after CR. The COPD group had greater functional decline than the HF group (6MWD, p = .006). Dyspnea was lower ( p = .001) and QoL higher ( p = .006) in the HF group. Mean NT-proBNP was higher in the HF group at all time points. FEV improved over 12 months in both groups ( p = .01). Mortality was 8.9%, 16.7%, and 37.8% at 12, 24, and 60 months, respectively. One-year predictors of mortality were baseline total steps (<3,000/day), 6MWD (<229 meters), and NT-proBNP level (>2,000 mg/pg).

Conclusions: In very severe COPD and HF, risks of mortality over 12 months can predict patients unlikely to benefit from CR and should be considered at initial referral.

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References
1.
Jolly K, Taylor R, Lip G, Davies M, Davis R, Mant J . A randomized trial of the addition of home-based exercise to specialist heart failure nurse care: the Birmingham Rehabilitation Uptake Maximisation study for patients with Congestive Heart Failure (BRUM-CHF) study. Eur J Heart Fail. 2009; 11(2):205-13. PMC: 2639417. DOI: 10.1093/eurjhf/hfn029. View

2.
Waatevik M, Johannessen A, Real F, Aanerud M, Hardie J, Bakke P . Oxygen desaturation in 6-min walk test is a risk factor for adverse outcomes in COPD. Eur Respir J. 2016; 48(1):82-91. DOI: 10.1183/13993003.00975-2015. View

3.
Louvaris Z, Vogiatzis I . Physiological basis of cardiopulmonary rehabilitation in patients with lung or heart disease. Breathe (Sheff). 2015; 11(2):120-7. PMC: 4487369. DOI: 10.1183/20734735.021114. View

4.
Durheim M, Smith P, Babyak M, Mabe S, Martinu T, Welty-Wolf K . Six-minute-walk distance and accelerometry predict outcomes in chronic obstructive pulmonary disease independent of Global Initiative for Chronic Obstructive Lung Disease 2011 Group. Ann Am Thorac Soc. 2015; 12(3):349-56. PMC: 4418313. DOI: 10.1513/AnnalsATS.201408-365OC. View

5.
Kazis L, Miller D, Clark J, Skinner K, Lee A, Rogers W . Health-related quality of life in patients served by the Department of Veterans Affairs: results from the Veterans Health Study. Arch Intern Med. 1998; 158(6):626-32. DOI: 10.1001/archinte.158.6.626. View