Adrenal Ganglioneuroblastoma in an Adult: A Rare Case Report

Overview

Journal Int J Endocrinol Metab

Publisher Brieflands

Specialty Endocrinology

Date 2018 Apr 27

PMID 29696040

Citations 6

Authors

Zahra Heidari

Mahmoud Ali Kaykhaei

Mahdi Jahantigh

Vahid Sheikhi

Affiliations

Soon will be listed here.

Abstract

Ganglioneuroblastoma is a primary malignant tumor of the sympathetic nervous system. It usually occurs in children and is extremely rare in adults. Here, we report a case of an adrenal ganglioneuroblastoma in a 38-year-old man. The adrenal incidentaloma was surgically removed and pathologically diagnosed as a ganglioneuroblastoma. The characteristics were described, because it is an unusual tumor based on the published reports in adults. To the best of our knowledge, fewer than 50 cases of ganglioneuroblastoma and 19 cases of adrenal ganglioneuroblastoma, including this case, are reported in the literature.

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References

Gunlusoy B, Arslan M, Selek E, Sural S, Ayder A . A case report: adrenal ganglioneuroblastoma in a 59-year old man. Int Urol Nephrol. 2005; 36(4):481-3. DOI: 10.1007/s11255-004-0851-z. View

Shimada H, Umehara S, Monobe Y, Hachitanda Y, Nakagawa A, Goto S . International neuroblastoma pathology classification for prognostic evaluation of patients with peripheral neuroblastic tumors: a report from the Children's Cancer Group. Cancer. 2001; 92(9):2451-61. DOI: 10.1002/1097-0142(20011101)92:9<2451::aid-cncr1595>3.0.co;2-s. View

Mizuno S, Iida T, Fujita S . Adult-onset adrenal ganglioneuroblastoma - Bone metastasis two years after surgery: report of a case. Surg Today. 2010; 40(5):482-6. DOI: 10.1007/s00595-008-4084-0. View

Matthay K . Neuroblastoma: biology and therapy. Oncology (Williston Park). 1998; 11(12):1857-66; discussion 1869-72, 1875. View

Ding X, Hou Y, Ma X, Huipeng Z, Wang C, Wang Y . Adult adrenal ganglioneuroblastoma: A rare case report. Can Urol Assoc J. 2015; 9(1-2):e75-7. PMC: 4336042. DOI: 10.5489/cuaj.2410. View

Mehta N, Tripathi R, Popli M, Nijhawan V . Bilateral intraabdominal ganglioneuroblastoma in an adult. Br J Radiol. 1997; 70:96-8. DOI: 10.1259/bjr.70.829.9059304. View

Brodeur G, Pritchard J, Berthold F, Carlsen N, Castel V, Castelberry R . Revisions of the international criteria for neuroblastoma diagnosis, staging, and response to treatment. J Clin Oncol. 1993; 11(8):1466-77. DOI: 10.1200/JCO.1993.11.8.1466. View

Peuchmaur M, DAmore E, Joshi V, Hata J, Roald B, Dehner L . Revision of the International Neuroblastoma Pathology Classification: confirmation of favorable and unfavorable prognostic subsets in ganglioneuroblastoma, nodular. Cancer. 2003; 98(10):2274-81. DOI: 10.1002/cncr.11773. View

Cameron D, Warner H, Szabo A . Chronic diarrhea in an adult with hypokalemic nephropathy and osteomalacia due to functioning ganglioneuroblastoma. Am J Med Sci. 1967; 253(4):417-24. DOI: 10.1097/00000441-196704000-00004. View

10.

Bolzacchini E, Martinelli B, Pinotti G . Adult onset of ganglioneuroblastoma of the adrenal gland: case report and review of the literature. Surg Case Rep. 2015; 1:79. PMC: 4567593. DOI: 10.1186/s40792-015-0062-0. View

11.

Gupta R, Dinda A . Ganglioneuroma of the adrenal gland: a rare case. Indian J Pathol Microbiol. 2008; 50(4):782-4. View

12.

Cotterill S, Pearson A, Pritchard J, Foot A, Roald B, Kohler J . Clinical prognostic factors in 1277 patients with neuroblastoma: results of The European Neuroblastoma Study Group 'Survey' 1982-1992. Eur J Cancer. 2000; 36(7):901-8. DOI: 10.1016/s0959-8049(00)00058-7. View

13.

Louis D, Ohgaki H, Wiestler O, Cavenee W, Burger P, Jouvet A . The 2007 WHO classification of tumours of the central nervous system. Acta Neuropathol. 2007; 114(2):97-109. PMC: 1929165. DOI: 10.1007/s00401-007-0243-4. View

14.

Leavitt J, Harold D, Robinson R . Adrenal ganglioneuroma: a familial case. Urology. 2000; 56(3):508. DOI: 10.1016/s0090-4295(00)00695-6. View

15.

Fujiwara T, Kawamura M, Sasou S, Hiramori K . Results of surgery for a compound adrenal tumor consisting of pheochromocytoma and ganglioneuroblastoma in an adult: 5-year follow-up. Intern Med. 2000; 39(1):58-62. DOI: 10.2169/internalmedicine.39.58. View

16.

Koizumi T, Kanbayashi T, Ichiyoshi T, Nakamura M, Moriyama S . Ganglioneuroblastoma with disseminated bone marrow infiltration in an adult. Intern Med. 1992; 31(11):1322-4. DOI: 10.2169/internalmedicine.31.1322. View

17.

Morris J, Shcochat S, SMITH E, Look A, Brodeur G, Cantor A . Biological variables in thoracic neuroblastoma: a Pediatric Oncology Group study. J Pediatr Surg. 1995; 30(2):296-302; discussion 302-3. DOI: 10.1016/0022-3468(95)90577-4. View

18.

Lonergan G, Schwab C, Suarez E, Carlson C . Neuroblastoma, ganglioneuroblastoma, and ganglioneuroma: radiologic-pathologic correlation. Radiographics. 2002; 22(4):911-34. DOI: 10.1148/radiographics.22.4.g02jl15911. View

19.

Qiu W, Li T, Sun X, Lv G . Onset of adrenal ganglioneuroblastoma in an adult after delivery. Ann Surg Treat Res. 2015; 89(4):220-3. PMC: 4595823. DOI: 10.4174/astr.2015.89.4.220. View

20.

Rousseau P, Bernard A, Favre J, Arnould L, Cheynel N, Manuelian M . [Ganglioneuroblastoma in the adult]. Presse Med. 1998; 27(33):1677-9. View