» Articles » PMID: 29682240

Extending the Range of Differential Diagnosis of Chronic Traumatic Encephalopathy of the Boxer: Insights from a Case Report

Overview
Date 2018 Apr 24
PMID 29682240
Citations 2
Authors
Affiliations
Soon will be listed here.
Abstract

Sports activities associated with repetitive cranial trauma have become a fad and are popular in gyms and even among children. It is important to consistently characterize the consequences of such sports activities in order to better advise society on the real risks to the central nervous system. We present the case of a former boxer reporting cognitive and behavioral symptoms that began six years after his retirement as a boxer, evolving progressively with parkinsonian and cerebellar features suggestive of probable chronic traumatic encephalopathy (CTE). Using our case as a paradigm, we extended the range of differential diagnosis of CTE, including corticobasal degeneration, multiple system atrophy, vitamin B12 deficiency, neurosyphilis, frontotemporal dementia and Alzheimer's disease.

Citing Articles

Pharmacological interventions in corticobasal degeneration: a review.

Caixeta L, Caixeta V, Nogueira Y, Aversi-Ferreira T Dement Neuropsychol. 2020; 14(3):243-247.

PMID: 32973978 PMC: 7500816. DOI: 10.1590/1980-57642020dn14-030006.


Emerging advances of in vivo detection of chronic traumatic encephalopathy and traumatic brain injury.

Dallmeier J, Meysami S, Merrill D, Raji C Br J Radiol. 2019; 92(1101):20180925.

PMID: 31287716 PMC: 6732918. DOI: 10.1259/bjr.20180925.

References
1.
Mendez M . What is the Relationship of Traumatic Brain Injury to Dementia?. J Alzheimers Dis. 2017; 57(3):667-681. DOI: 10.3233/JAD-161002. View

2.
Parmera J, Rodriguez R, Studart Neto A, Nitrini R, Brucki S . Corticobasal syndrome: A diagnostic conundrum. Dement Neuropsychol. 2017; 10(4):267-275. PMC: 5619264. DOI: 10.1590/s1980-5764-2016dn1004003. View

3.
Collins-Praino L, Corrigan F . Does neuroinflammation drive the relationship between tau hyperphosphorylation and dementia development following traumatic brain injury?. Brain Behav Immun. 2016; 60:369-382. DOI: 10.1016/j.bbi.2016.09.027. View

4.
Jordan B . Chronic traumatic brain injury associated with boxing. Semin Neurol. 2000; 20(2):179-85. DOI: 10.1055/s-2000-9826. View

5.
Iverson G, Gardner A, McCrory P, Zafonte R, Castellani R . A critical review of chronic traumatic encephalopathy. Neurosci Biobehav Rev. 2015; 56:276-93. DOI: 10.1016/j.neubiorev.2015.05.008. View