A PRISMA Systematic Review and Meta-analysis on Chlamydia Trachomatis Infections in Iranian Women (1986-2015)

Overview

Journal Medicine (Baltimore)

Specialty General Medicine

Date 2018 Apr 19

PMID 29668583

Citations 2

Authors

Daem Roshani

Rashid Ramazanzadeh

Fariba Farhadifar

Amjad Ahmadi

Safoura Derakhshan

Samaneh Rouhi

Shamsi Zarea

Farnaz Zandvakili

Affiliations

Soon will be listed here.

Abstract

Background: Chlamydia trachomatis (CT) is the cause of genital tract infections in women. Some evidence has shown the role of this infection with CT in spontaneous abortions. The purpose of this study is to study the frequency of CT infection in Iranian women.

Methods: This study was performed based on PRISMA guidelines. A total of 75 articles published in Google Scholar, PubMed, ISI Web of Science, Biological abs, Iranmedex, SID, and Scopus databases were found (1986-2015) using the following keywords: CT in women, CT and Iranian women, CT and infection in Iran, CT and pregnancy in Iran, CT and preterm delivery in Iran, CT and preterm labor in Iran, CT and fertility in Iran, CT and infertility in Iran, and CT and abortion in Iran. Finally, 40 studies from different regions of Iran were included. Statistical analyses were performed using R3 and STATA 12.

Results: From 1986 to 2015, the lowest rate of prevalence was from 2010 to 2011 (3.9%) and the highest prevalence rate was in 2009 (69.39%) in northern Iran. Fixed effects for different parts of Iran (North, South, East, and West) were Pooled proportion: 0.13 (95% confidence interval [CI] = 0.12-0.14) and for samples (cervical, vaginal, urine, and blood) the pooled proportion was = 0.14 (95% CI = 0.12-0.14).

Conclusion: CT infection in this study was prevalent in urine samples and the rate of CT was observed from culture methods in comparison to other methods. Because women with CT play an important role because of sexual activity for transmission and untreated women are at risk of developing sequels. Also, most studies in Iran use sensitive polymerase chain reaction tests for the detection of genital CT infections.

Citing Articles

The role of in preterm delivery: a case-control study in Besat Hospital, Sanandaj, Iran (2018-2019).

Ahmadi S, Farhadifar F, Sharami S, Zare S, Rezaei M, Soofizadeh N Iran J Microbiol. 2020; 12(4):325-330.

PMID: 32994904 PMC: 7502151. DOI: 10.18502/ijm.v12i4.3936.

Prevalence of Ureaplasma urealyticum, Chlamydia trachomatis, and Neisseria gonorrhoeae in gynecological outpatients, Taizhou, China.

Cai S, Pan J, Duan D, Yu C, Yang Z, Zou J J Clin Lab Anal. 2019; 34(2):e23072.

PMID: 31675147 PMC: 7031556. DOI: 10.1002/jcla.23072.

References

Adams E, Charlett A, Edmunds W, Hughes G . Chlamydia trachomatis in the United Kingdom: a systematic review and analysis of prevalence studies. Sex Transm Infect. 2004; 80(5):354-62. PMC: 1744901. DOI: 10.1136/sti.2003.005454. View

Vu Nguyen T, Van Khuu N, Thi Le T, Nguyen A, Cao V, Tham D . Sexually transmitted infections and risk factors for gonorrhea and chlamydia in female sex workers in Soc Trang, Vietnam. Sex Transm Dis. 2008; 35(11):935-40. PMC: 2903543. DOI: 10.1097/OLQ.0b013e3181812d03. View

Hajikhani B, Motallebi T, Norouzi J, Bahador A, Bagheri R, Asgari S . Classical and Molecular Methods for Evaluation of Chlamydia trachomatis Infection in Women with Tubal Factor Infertility. J Reprod Infertil. 2013; 14(1):29-33. PMC: 3719367. View

Bakhtiari A, Firoozjahi A . Chlamydia trachomatis infection in women attending health centres in Babol: prevalence and risk factors. East Mediterr Health J. 2008; 13(5):1124-31. DOI: 10.26719/2007.13.5.1124. View

Fatholahzadeh B, Bahador A, Haghighi Hasanabad M, Bazarjani F, Haghighi F . Comparative screening of Chlamydia trachomatis infection in women population in tehran, iran. Iran Red Crescent Med J. 2012; 14(5):289-93. PMC: 3398636. View

Naserpour Farivar T, Johari P . Lack of association between Chlamydia trachomatis infection and cervical cancer--Taq Man realtime PCR assay findings. Asian Pac J Cancer Prev. 2012; 13(8):3701-4. DOI: 10.7314/apjcp.2012.13.8.3701. View

Silveira M, Ghanem K, Erbelding E, Burke A, Johnson H, Singh R . Chlamydia trachomatis infection during pregnancy and the risk of preterm birth: a case-control study. Int J STD AIDS. 2009; 20(7):465-9. DOI: 10.1258/ijsa.2008.008388. View

Kataoka S, Yamada T, Chou K, Nishida R, Morikawa M, Minami M . Association between preterm birth and vaginal colonization by mycoplasmas in early pregnancy. J Clin Microbiol. 2006; 44(1):51-5. PMC: 1351938. DOI: 10.1128/JCM.44.1.51-55.2006. View

Sciarra J . Sexually transmitted diseases: global importance. Int J Gynaecol Obstet. 1997; 58(1):107-19. DOI: 10.1016/s0020-7292(97)02867-1. View

10.

Duncan B, Hart G . Sexuality and health: the hidden costs of screening for Chlamydia trachomatis. BMJ. 1999; 318(7188):931-3. PMC: 1115345. DOI: 10.1136/bmj.318.7188.931. View

11.

Hanski L, Vuorela P . Lead Discovery Strategies for Identification of Chlamydia pneumoniae Inhibitors. Microorganisms. 2016; 4(4). PMC: 5192526. DOI: 10.3390/microorganisms4040043. View

12.

Cook R, Hutchison S, Ostergaard L, Braithwaite R, Ness R . Systematic review: noninvasive testing for Chlamydia trachomatis and Neisseria gonorrhoeae. Ann Intern Med. 2005; 142(11):914-25. DOI: 10.7326/0003-4819-142-11-200506070-00010. View

13.

Marashi S, Moulana Z, Fooladi A, Mashhadi Karim M . Comparison of Genital Chlamydia trachomatis Infection Incidence Between Women With Infertility and Healthy Women in Iran Using PCR and Immunofluorescence Methods. Jundishapur J Microbiol. 2014; 7(4):e9450. PMC: 4138628. DOI: 10.5812/jjm.9450. View

14.

Moher D, Liberati A, Tetzlaff J, Altman D . Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. PLoS Med. 2009; 6(7):e1000097. PMC: 2707599. DOI: 10.1371/journal.pmed.1000097. View

15.

Jenab A, Roghanian R, Golbang N, Golbang P, Chamani-Tabriz L . Comparison of three methods of DNA extraction in endocervical specimens for Chlamydia trachomatis infection by spectrophotometry, agarose gel, and PCR. Arch Immunol Ther Exp (Warsz). 2010; 58(3):227-34. DOI: 10.1007/s00005-010-0076-z. View

16.

Afrakhteh M, Mahdavi A, Beyhaghi H, Moradi A, Gity S, Zafargandi S . The prevalence of Chlamydia trachomatis in patients who remained symptomatic after completion of sexually transmitted infection treatment. Iran J Reprod Med. 2014; 11(4):285-92. PMC: 3941430. View

17.

Lewis D, Newton D, Guy R, Ali H, Chen M, Fairley C . The prevalence of Chlamydia trachomatis infection in Australia: a systematic review and meta-analysis. BMC Infect Dis. 2012; 12:113. PMC: 3462140. DOI: 10.1186/1471-2334-12-113. View

18.

Watson E, Templeton A, Russell I, Paavonen J, Mardh P, Stary A . The accuracy and efficacy of screening tests for Chlamydia trachomatis: a systematic review. J Med Microbiol. 2002; 51(12):1021-1031. DOI: 10.1099/0022-1317-51-12-1021. View

19.

Hossein Rashidi B, Chamani-Tabriz L, Haghollahi F, Jeddi-Tehrani M, Naghizadeh M, Shariat M . Effects of Chlamydia trachomatis Infection on Fertility; A Case-Control Study. J Reprod Infertil. 2013; 14(2):67-72. PMC: 3719322. View

20.

Naderi T, Kazerani F, Bahraminpoor A . Comparison of chlamydia infection prevalence between patients with and without ectopic pregnancy using the PCR method. Ginekol Pol. 2013; 83(11):819-21. View