Osia B, Merkell A, Lopezcolorado F, Ping X, Stark J
PLoS Genet. 2024; 20(11):e1011479.
PMID: 39561207
PMC: 11614213.
DOI: 10.1371/journal.pgen.1011479.
Wang B, Kou H, Wang Y, Zhang Q, Jiang D, Wang J
Cell Death Dis. 2024; 15(10):761.
PMID: 39426946
PMC: 11490576.
DOI: 10.1038/s41419-024-07116-4.
Kim S, Park S, Kang N, Ra J, Myung K, Lee K
Nucleic Acids Res. 2024; 52(19):11785-11805.
PMID: 39291733
PMC: 11514459.
DOI: 10.1093/nar/gkae785.
Reis-Cunha J, Pimenta-Carvalho S, Almeida L, Coqueiro-Dos-Santos A, Marques C, Black J
Genome Res. 2024; 34(3):441-453.
PMID: 38604731
PMC: 11067883.
DOI: 10.1101/gr.278550.123.
Muoio D, Laspata N, Dannenberg R, Curry C, Darkoa-Larbi S, Hedglin M
Nat Commun. 2024; 15(1):2857.
PMID: 38565848
PMC: 10987537.
DOI: 10.1038/s41467-024-47222-7.
Distinct modes of telomere synthesis and extension contribute to Alternative Lengthening of Telomeres.
Lu R, Nelson C, Rogers S, Cesare A, Sobinoff A, Pickett H
iScience. 2024; 27(1):108655.
PMID: 38213617
PMC: 10783591.
DOI: 10.1016/j.isci.2023.108655.
MutSβ protects common fragile sites by facilitating homology-directed repair at DNA double-strand breaks with secondary structures.
Li Y, Zhang Y, Shah S, Chang C, Wang H, Wu X
Nucleic Acids Res. 2023; 52(3):1120-1135.
PMID: 38038265
PMC: 10853791.
DOI: 10.1093/nar/gkad1112.
Mitotic DNA Synthesis in Untransformed Human Cells Preserves Common Fragile Site Stability via a FANCD2-Driven Mechanism That Requires HELQ.
Traband E, Hammerlund S, Shameem M, Narayan A, Ramana S, Tella A
J Mol Biol. 2023; 435(22):168294.
PMID: 37777152
PMC: 10839910.
DOI: 10.1016/j.jmb.2023.168294.
Genome maintenance meets mechanobiology.
Spegg V, Altmeyer M
Chromosoma. 2023; 133(1):15-36.
PMID: 37581649
PMC: 10904543.
DOI: 10.1007/s00412-023-00807-5.
The DHX9 helicase interacts with human DNA polymerase δ4 and stimulates its activity in D-loop extension synthesis.
Wang X, Zhang S, Zhang Z, Mazloum N, Lee E, Lee M
DNA Repair (Amst). 2023; 128:103513.
PMID: 37285751
PMC: 10330758.
DOI: 10.1016/j.dnarep.2023.103513.
ATRX/DAXX: Guarding the Genome against the Hazards of ALT.
Clatterbuck Soper S, Meltzer P
Genes (Basel). 2023; 14(4).
PMID: 37107548
PMC: 10137841.
DOI: 10.3390/genes14040790.
Pathway choice in the alternative telomere lengthening in neoplasia is dictated by replication fork processing mediated by EXD2's nuclease activity.
Broderick R, Cherdyntseva V, Nieminuszczy J, Dragona E, Kyriakaki M, Evmorfopoulou T
Nat Commun. 2023; 14(1):2428.
PMID: 37105990
PMC: 10140042.
DOI: 10.1038/s41467-023-38029-z.
Homology directed telomere clustering, ultrabright telomere formation and nuclear envelope rupture in cells lacking TRF2 and RAP1.
Rai R, Biju K, Sun W, Sodeinde T, Al-Hiyasat A, Morgan J
Nat Commun. 2023; 14(1):2144.
PMID: 37059728
PMC: 10104862.
DOI: 10.1038/s41467-023-37761-w.
The Molecular Mechanisms and Therapeutic Prospects of Alternative Lengthening of Telomeres (ALT).
Sohn E, Goralsky J, Shay J, Min J
Cancers (Basel). 2023; 15(7).
PMID: 37046606
PMC: 10093677.
DOI: 10.3390/cancers15071945.
Telomere Fragility and MiDAS: Managing the Gaps at the End of the Road.
Barnes R, Thosar S, Opresko P
Genes (Basel). 2023; 14(2).
PMID: 36833275
PMC: 9956152.
DOI: 10.3390/genes14020348.
Mitotic DNA synthesis in response to replication stress requires the sequential action of DNA polymerases zeta and delta in human cells.
Wu W, Barwacz S, Bhowmick R, Lundgaard K, Goncalves Dinis M, Clausen M
Nat Commun. 2023; 14(1):706.
PMID: 36759509
PMC: 9911744.
DOI: 10.1038/s41467-023-35992-5.
PRIMPOL competes with RAD51 to resolve G-quadruplex-induced replication stress via its interaction with RPA.
Li T, Tang L, Kou H, Wang F
Acta Biochim Biophys Sin (Shanghai). 2023; 55(3):498-507.
PMID: 36647718
PMC: 10160237.
DOI: 10.3724/abbs.2022165.
FANCD2 promotes mitotic rescue from transcription-mediated replication stress in SETX-deficient cancer cells.
Said M, Barra V, Balzano E, Talhaoui I, Pelliccia F, Giunta S
Commun Biol. 2022; 5(1):1395.
PMID: 36543851
PMC: 9772326.
DOI: 10.1038/s42003-022-04360-2.
Replication stress generates distinctive landscapes of DNA copy number alterations and chromosome scale losses.
Shaikh N, Mazzagatti A, De Angelis S, Johnson S, Bakker B, Spierings D
Genome Biol. 2022; 23(1):223.
PMID: 36266663
PMC: 9583511.
DOI: 10.1186/s13059-022-02781-0.
TERRA and RAD51AP1 promote alternative lengthening of telomeres through an R- to D-loop switch.
Yadav T, Zhang J, Ouyang J, Leung W, Simoneau A, Zou L
Mol Cell. 2022; 82(21):3985-4000.e4.
PMID: 36265486
PMC: 9637728.
DOI: 10.1016/j.molcel.2022.09.026.