» Articles » PMID: 29642970

Work Aggravated Asthma in Great Britain: a Cross-sectional Postal Survey

Overview
Date 2018 Apr 13
PMID 29642970
Citations 5
Authors
Affiliations
Soon will be listed here.
Abstract

Objective: Work aggravated asthma (WAA), asthma made worse by but not caused by workplace exposures, can have a negative impact on personal, social, financial and societal costs. There is limited data on prevalence levels of WAA in Great Britain (GB). The objective of this study was to estimate the prevalence of WAA in GB, and to assess its potential causes.Materials and methodsA cross-sectional postal questionnaire study was carried out. A total of 1620 questionnaires were sent to three populations of adults with asthma. The questionnaire recorded; demographic details, current job, self-reported health status, presence of asthma and respiratory symptoms, duration and severity of symptoms and medication requirements. Questions relating to work environment and employers' actions were included, and each participant completed an assessment of health-related quality of life using the EuroQol Research Foundation EQ-5D.

Results: There were 207 completed questionnaires; response rates were 6% primary care, 45% secondary care and 71% Asthma UK. This represented a 13% overall response rate. Self-reported prevalence of WAA was 33% (95% CI 24.4-41.6%). In all, 19% of workers had changed their job because of breathing problems. Workers with WAA reported higher levels of work-related stress. Quality of life using the EQ-5D utility index was lower in those with WAA.

Conclusion: WAA is a common problem in asthmatics in GB. This result is in keeping with international prevalence rates. Further research could assist the understanding of the most significant aggravants to asthma at work and help define appropriate interventions by workplaces.

Citing Articles

Validity and Responsiveness of EQ-5D in Asthma: A Systematic Review and Meta-analysis.

Chua A, Cheng L, Soh Z, Chen L, Luo N Patient. 2024; 18(1):35-47.

PMID: 39243353 DOI: 10.1007/s40271-024-00711-9.


PROMIS Scales for Assessment of Persistent Post-COVID Symptoms: A Cross Sectional Study.

Ganesh R, Ghosh A, Nyman M, Croghan I, Grach S, Anstine C J Prim Care Community Health. 2021; 12:21501327211030413.

PMID: 34231395 PMC: 8267017. DOI: 10.1177/21501327211030413.


Causes and Phenotypes of Work-Related Asthma.

Maestrelli P, Henneberger P, Tarlo S, Mason P, Boschetto P Int J Environ Res Public Health. 2020; 17(13).

PMID: 32627764 PMC: 7369698. DOI: 10.3390/ijerph17134713.


Transforming growth factor-β1 and eosinophil-derived neurotoxins contribute to the development of work-related respiratory symptoms in bakery workers.

Trinh H, Ulambayar B, Cao T, Yang E, Lee S, Park H World Allergy Organ J. 2019; 12(9):100058.

PMID: 31641406 PMC: 6796779. DOI: 10.1016/j.waojou.2019.100058.


Update on the Management of Occupational Asthma and Work-Exacerbated Asthma.

Lau A, Tarlo S Allergy Asthma Immunol Res. 2019; 11(2):188-200.

PMID: 30661311 PMC: 6340795. DOI: 10.4168/aair.2019.11.2.188.


References
1.
Fishwick D, Sen D, Barker P, Codling A, Fox D, Naylor S . Health surveillance for occupational asthma in the UK. Occup Med (Lond). 2016; 66(5):365-70. PMC: 4913369. DOI: 10.1093/occmed/kqw028. View

2.
Nohr E, Frydenberg M, Henriksen T, Olsen J . Does low participation in cohort studies induce bias?. Epidemiology. 2006; 17(4):413-8. DOI: 10.1097/01.ede.0000220549.14177.60. View

3.
Fishwick D . Work aggravated asthma; a review of the recent evidence. Br Med Bull. 2014; 110(1):77-88. DOI: 10.1093/bmb/ldu004. View

4.
Knoeller G, Mazurek J, Moorman J . Health-related quality of life among adults with work-related asthma in the United States. Qual Life Res. 2012; 22(4):771-80. PMC: 4578634. DOI: 10.1007/s11136-012-0206-7. View

5.
Tarlo S, Liss G, Blanc P . How to diagnose and treat work-related asthma: key messages for clinical practice from the American college of chest physicians consensus statement. Pol Arch Med Wewn. 2009; 119(10):660-6. View