Synthesis of Au@polymer Nanohybrids with Transited Core-shell Morphology from Concentric to Eccentric Emoji-N or Janus Nanoparticles

Overview

Journal Sci Rep

Specialty Science

Date 2018 Apr 12

PMID 29636519

Citations 3

Authors

Nekane Guarrotxena

Olga Garcia

Isabel Quijada-Garrido

Affiliations

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Abstract

The combination of multifunctionality and synergestic effect displayed by hybrid nanoparticles (NPs) has been revealed as an effective stratagem in the development of advanced nanostructures with unique biotechnology and optoelectronic applications. Although important work has been devoted, the demand of facile, versatile and efficient synthetic approach remains still challenging. Herein, we report a feasible and innovative way for polymer-shell assembling onto gold nanoparticles in competitive conditions of hydrophobic/hydrophilic feature and interfacial energy of components to generate core-shell nanohybrids with singular morphologies. The fine control of reaction parameters allows a modulated transformation from concentric to eccentric nanostructure-geometries. In this regard, a rational selection of the components and solvent ratio guarantee the reproducibility and efficiency on hybrid-nanoassembly. Furthermore, the simplicity of the synthetic approach offers the possibility to obtain asymmetric Janus NPs and new morphologies (quizzical-aspheric polymer-shell, named Emoji-N-hybrids) with adjustable surface-coating, leading to new properties and applications that are unavailable to their symmetrical or single components.

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References

Hu H, Ji F, Xu Y, Yu J, Liu Q, Chen L . Reversible and Precise Self-Assembly of Janus Metal-Organosilica Nanoparticles through a Linker-Free Approach. ACS Nano. 2016; 10(8):7323-30. DOI: 10.1021/acsnano.6b03396. View

Wang Y, Ding T, Baumberg J, Smoukov S . Symmetry breaking polymerization: one-pot synthesis of plasmonic hybrid Janus nanoparticles. Nanoscale. 2015; 7(23):10344-9. DOI: 10.1039/c5nr01999k. View

Mai Y, Eisenberg A . Self-assembly of block copolymers. Chem Soc Rev. 2012; 41(18):5969-85. DOI: 10.1039/c2cs35115c. View

Liu C, Chen G, Sun H, Xu J, Feng Y, Zhang Z . Toroidal micelles of polystyrene- block -poly(acrylic acid). Small. 2011; 7(19):2721-6. DOI: 10.1002/smll.201100443. View

Ding T, Smoukov S, Baumberg J . Harnessing nonlinear rubber swelling for bulk synthesis of anisotropic hybrid nanoparticles. J Mater Chem C Mater. 2016; 2(41):8745-8749. PMC: 4894071. DOI: 10.1039/c4tc01660b. View

Xia Y, Xiong Y, Lim B, Skrabalak S . Shape-controlled synthesis of metal nanocrystals: simple chemistry meets complex physics?. Angew Chem Int Ed Engl. 2008; 48(1):60-103. PMC: 2791829. DOI: 10.1002/anie.200802248. View

Chen T, Yang M, Wang X, Tan L, Chen H . Controlled assembly of eccentrically encapsulated gold nanoparticles. J Am Chem Soc. 2008; 130(36):11858-9. DOI: 10.1021/ja8040288. View

Bodelon G, Montes-Garcia V, Fernandez-Lopez C, Pastoriza-Santos I, Perez-Juste J, Liz-Marzan L . Au@pNIPAM SERRS Tags for Multiplex Immunophenotyping Cellular Receptors and Imaging Tumor Cells. Small. 2015; 11(33):4149-57. DOI: 10.1002/smll.201500269. View

Zhang J, Ma N, Tang F, Cui Q, He F, Li L . pH- and glucose-responsive core-shell hybrid nanoparticles with controllable metal-enhanced fluorescence effects. ACS Appl Mater Interfaces. 2012; 4(3):1747-51. DOI: 10.1021/am201858u. View

10.

Zhu L, Wang H, Shen X, Chen L, Wang Y, Chen H . Developing mutually encapsulating materials for versatile syntheses of multilayer metal-silica-polymer hybrid nanostructures. Small. 2012; 8(12):1857-62. DOI: 10.1002/smll.201102670. View

11.

Geng J, Li K, Pu K, Ding D, Liu B . Conjugated polymer and gold nanoparticle co-loaded PLGA nanocomposites with eccentric internal nanostructure for dual-modal targeted cellular imaging. Small. 2012; 8(15):2421-9. DOI: 10.1002/smll.201102353. View

12.

Cai T, Marquez M, Hu Z . Monodisperse thermoresponsive microgels of poly(ethylene glycol) analogue-based biopolymers. Langmuir. 2007; 23(17):8663-6. DOI: 10.1021/la700923r. View

13.

Zhang L, Chen Y, Li Z, Li L, Saint-Cricq P, Li C . Tailored Synthesis of Octopus-type Janus Nanoparticles for Synergistic Actively-Targeted and Chemo-Photothermal Therapy. Angew Chem Int Ed Engl. 2016; 55(6):2118-21. DOI: 10.1002/anie.201510409. View

14.

Li L, Zhang L, Xing S, Wang T, Luo S, Zhang X . Generalized approach to the synthesis of reversible concentric and eccentric polymer-coated nanostructures. Small. 2012; 9(6):825-30. DOI: 10.1002/smll.201201735. View

15.

Chaudhuri R, Paria S . Core/shell nanoparticles: classes, properties, synthesis mechanisms, characterization, and applications. Chem Rev. 2011; 112(4):2373-433. DOI: 10.1021/cr100449n. View

16.

Karg M, Pastoriza-Santos I, Perez-Juste J, Hellweg T, Liz-Marzan L . Nanorod-coated PNIPAM microgels: thermoresponsive optical properties. Small. 2007; 3(7):1222-9. DOI: 10.1002/smll.200700078. View

17.

Ohnuma A, Cho E, Jiang M, Ohtani B, Xia Y . Metal-polymer hybrid colloidal particles with an eccentric structure. Langmuir. 2009; 25(24):13880-7. DOI: 10.1021/la9015146. View

18.

Pelton R . Temperature-sensitive aqueous microgels. Adv Colloid Interface Sci. 2000; 85(1):1-33. DOI: 10.1016/s0001-8686(99)00023-8. View

19.

Zhang M, Ngo T, Rabiah N, Otanicar T, Phelan P, Swaminathan R . Core-shell and asymmetric polystyrene-gold composite particles via one-step Pickering emulsion polymerization. Langmuir. 2013; 30(1):75-82. DOI: 10.1021/la4041166. View

20.

Ohnuma A, Cho E, Camargo P, Au L, Ohtani B, Xia Y . A facile synthesis of asymmetric hybrid colloidal particles. J Am Chem Soc. 2009; 131(4):1352-3. PMC: 2640490. DOI: 10.1021/ja8079934. View