Regulatory Mechanisms of Branching Morphogenesis in Mouse Submandibular Gland Rudiments

Overview

Journal Jpn Dent Sci Rev

Publisher Elsevier

Specialty Dentistry

Date 2018 Apr 10

PMID 29628996

Citations 3

Authors

Masanori Kashimata

Toru Hayashi

Affiliations

Soon will be listed here.

Abstract

Branching morphogenesis is an important developmental process for many organs, including the salivary glands. Whereas epithelial-mesenchymal interactions, which are cell-to-cell communications, are known to drive branching morphogenesis, the molecular mechanisms responsible for those inductive interactions are still largely unknown. Cell growth factors and integrins are known to be regulators of branching morphogenesis of salivary glands. In addition, functional microRNAs (miRNAs) have recently been reported to be present in the developing submandibular gland. In this review, the authors describe the roles of various cell growth factors, integrins and miRNAs in branching morphogenesis of developmental mouse submandibular glands.

Citing Articles

Inflationary theory of branching morphogenesis in the mouse salivary gland.

Bordeu I, Chatzeli L, Simons B Nat Commun. 2023; 14(1):3422.

PMID: 37296120 PMC: 10256724. DOI: 10.1038/s41467-023-39124-x.

Cryopreservation of Biologically Functional Submandibular Gland Rudiments from Fetal Mice.

Adachi K, Ohno Y, Satoh K, Shitara A, Muramathu Y, Kashimata M In Vivo. 2020; 34(6):3271-3277.

PMID: 33144433 PMC: 7811606. DOI: 10.21873/invivo.12164.

Single-Cell RNA-seq Identifies Cell Diversity in Embryonic Salivary Glands.

Sekiguchi R, Martin D, Yamada K J Dent Res. 2019; 99(1):69-78.

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