[Preanalytics and Biobanking : Influence of Preanalytical Factors on Tissue Sample Quality]

Overview

Journal Pathologe

Specialty Pathology

Date 2018 Apr 6

PMID 29619508

Authors

K-F Becker

J Wipperfurth

E Herpel

Affiliations

Soon will be listed here.

Abstract

Access to well-characterized human biosamples is one of the most important prerequisites for modern biomedical research. Biobanks play a decisive role here, as they provide corresponding biosamples for planned analyses. Many interfering factors influencing the quality of biosamples have to be taken into account. In addition to logistical, ethical, and data protection aspects, preanalytical variables in the context of sample acquisition, storage, and processing should be mentioned in particular. In this paper, therefore, the most important preanalytical influencing factors are presented systematically and an overview of current national and international activities for the standardized recording of these factors is provided with the goal of being able to better understand their influence on results and to minimize them in the near future.

References

Caixeiro N, Lai K, Lee C . Quality assessment and preservation of RNA from biobank tissue specimens: a systematic review. J Clin Pathol. 2015; 69(3):260-5. DOI: 10.1136/jclinpath-2015-203384. View

Kiehntopf M, Krawczak M . Biobanking and international interoperability: samples. Hum Genet. 2011; 130(3):369-76. DOI: 10.1007/s00439-011-1068-8. View

Livesey J, Ellis M, Evans M . Pre-analytical requirements. Clin Biochem Rev. 2008; 29 Suppl 1:S11-5. PMC: 2556574. View

Kokkat T, McGarvey D, Patel M, Tieniber A, LiVolsi V, Baloch Z . Protein extraction from methanol fixed paraffin embedded tissue blocks: A new possibility using cell blocks. Cytojournal. 2014; 10:23. PMC: 3869970. DOI: 10.4103/1742-6413.122299. View

Schrohl A, Wurtz S, Kohn E, Banks R, Nielsen H, Sweep F . Banking of biological fluids for studies of disease-associated protein biomarkers. Mol Cell Proteomics. 2008; 7(10):2061-6. PMC: 2559931. DOI: 10.1074/mcp.R800010-MCP200. View

Riegman P, Morente M, Betsou F, De Blasio P, Geary P . Biobanking for better healthcare. Mol Oncol. 2009; 2(3):213-22. PMC: 5527804. DOI: 10.1016/j.molonc.2008.07.004. View

Lydia Kynast K, Volk N, Fleming T, Herpel E . Diabetes-Associated Biobanking: More Topical Than Ever?. Exp Clin Endocrinol Diabetes. 2017; 125(9):603-609. DOI: 10.1055/s-0042-123039. View

Morrin H, Gunningham S, Currie M, Dachs G, Fox S, Robinson B . The Christchurch Tissue Bank to support cancer research. N Z Med J. 2005; 118(1225):U1735. View

Herpel E, Schmitt S, Kiehntopf M . [Quality of biomaterials in liquid- and tissue-biobanking]. Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 2016; 59(3):325-35. DOI: 10.1007/s00103-015-2294-3. View

10.

Espina V, Edmiston K, Heiby M, Pierobon M, Sciro M, Merritt B . A portrait of tissue phosphoprotein stability in the clinical tissue procurement process. Mol Cell Proteomics. 2008; 7(10):1998-2018. PMC: 2559936. DOI: 10.1074/mcp.M700596-MCP200. View

11.

Gundisch S, Hauck S, Sarioglu H, Schott C, Viertler C, Kap M . Variability of protein and phosphoprotein levels in clinical tissue specimens during the preanalytical phase. J Proteome Res. 2012; 11(12):5748-62. DOI: 10.1021/pr300560y. View

12.

Herpel E, Koleganova N, Schirmacher P . [Tissue bank of the National Centre for Tumour Disease. An innovative platform for translational tumour]. Pathologe. 2008; 29 Suppl 2:204-9. DOI: 10.1007/s00292-008-1067-2. View

13.

Wander K, Brindle E, OConnor K . C-reactive protein across the menstrual cycle. Am J Phys Anthropol. 2008; 136(2):138-46. DOI: 10.1002/ajpa.20785. View

14.

Carraro P, Plebani M . Errors in a stat laboratory: types and frequencies 10 years later. Clin Chem. 2007; 53(7):1338-42. DOI: 10.1373/clinchem.2007.088344. View

15.

Kokkat T, Patel M, McGarvey D, LiVolsi V, Baloch Z . Archived formalin-fixed paraffin-embedded (FFPE) blocks: A valuable underexploited resource for extraction of DNA, RNA, and protein. Biopreserv Biobank. 2014; 11(2):101-6. PMC: 4077003. DOI: 10.1089/bio.2012.0052. View

16.

Plebani M, Carraro P . Mistakes in a stat laboratory: types and frequency. Clin Chem. 1997; 43(8 Pt 1):1348-51. View

17.

Ellervik C, Vaught J . Preanalytical variables affecting the integrity of human biospecimens in biobanking. Clin Chem. 2015; 61(7):914-34. DOI: 10.1373/clinchem.2014.228783. View

18.

Ferguson R, Hochstrasser D, Banks R . Impact of preanalytical variables on the analysis of biological fluids in proteomic studies. Proteomics Clin Appl. 2010; 1(8):739-46. DOI: 10.1002/prca.200700380. View

19.

Riegman P, de Jong B, Daidone M, Soderstrom T, Thompson J, Hall J . Optimizing sharing of hospital biobank samples. Sci Transl Med. 2015; 7(297):297fs31. DOI: 10.1126/scitranslmed.3009279. View

20.

Gnanapragasam V . Unlocking the molecular archive: the emerging use of formalin-fixed paraffin-embedded tissue for biomarker research in urological cancer. BJU Int. 2009; 105(2):274-8. DOI: 10.1111/j.1464-410X.2009.08665.x. View