Zika Virus Infection in the Returning Traveller: What Every Neurologist Should Know

Overview

Journal Pract Neurol

Specialty Neurology

Date 2018 Apr 6

PMID 29618586

Citations 7

Authors

Sonja Emily Leonhard

Suzannah Lant

Bart C Jacobs

Annelies Wilder-Smith

Maria Lucia Brito Ferreira

Tom Solomon

Hugh John Willison

Affiliations

Soon will be listed here.

Abstract

Zika virus has been associated with a wide range of neurological complications. Neurologists in areas without current active transmission of the virus may be confronted with Zika-associated neurological disease, as a large number of returning travellers with Zika virus infection have been reported and the virus continues to spread to previously unaffected regions. This review provides an overview of Zika virus-associated neurological disease and aims to support neurologists who may encounter patients returning from endemic areas.

Citing Articles

HLA-A, HSPA5, IGFBP5 and PSMA2 Are Restriction Factors for Zika Virus Growth in Astrocytic Cells.

Sher A, Lao Y, Coombs K Viruses. 2023; 15(1).

PMID: 36680137 PMC: 9863221. DOI: 10.3390/v15010097.

Novel Therapeutic Nutrients Molecules That Protect against Zika Virus Infection with a Special Note on Palmitoleate.

Muthuraj P, Krishnamoorthy C, Anderson-Berry A, Hanson C, Natarajan S Nutrients. 2023; 15(1).

PMID: 36615782 PMC: 9823984. DOI: 10.3390/nu15010124.

Effector CD8 T Cell-Dependent Zika Virus Control in the CNS: A Matter of Time and Numbers.

Nazerai L, Scholler A, Bassi M, Buus S, Stryhn A, Christensen J Front Immunol. 2020; 11:1977.

PMID: 32973802 PMC: 7461798. DOI: 10.3389/fimmu.2020.01977.

ZikaPLAN: addressing the knowledge gaps and working towards a research preparedness network in the Americas.

Wilder-Smith A, Preet R, Brickley E, Ximenes R, Miranda-Filho D, Turchi Martelli C Glob Health Action. 2019; 12(1):1666566.

PMID: 31640505 PMC: 6818126. DOI: 10.1080/16549716.2019.1666566.

Incidence of Guillain-Barré Syndrome (GBS) in Latin America and the Caribbean before and during the 2015-2016 Zika virus epidemic: A systematic review and meta-analysis.

Capasso A, Ompad D, Vieira D, Wilder-Smith A, Tozan Y PLoS Negl Trop Dis. 2019; 13(8):e0007622.

PMID: 31449532 PMC: 6730933. DOI: 10.1371/journal.pntd.0007622.

References

Kaplin A, Krishnan C, Deshpande D, Pardo C, Kerr D . Diagnosis and management of acute myelopathies. Neurologist. 2005; 11(1):2-18. DOI: 10.1097/01.nrl.0000149975.39201.0b. View

Durbin A, Wilder-Smith A . An update on Zika vaccine developments. Expert Rev Vaccines. 2017; 16(8):781-787. DOI: 10.1080/14760584.2017.1345309. View

Soares C, Brasil P, Carrera R, Sequeira P, de Filippis A, Borges V . Fatal encephalitis associated with Zika virus infection in an adult. J Clin Virol. 2016; 83:63-5. DOI: 10.1016/j.jcv.2016.08.297. View

Nascimento O, Frontera J, Amitrano D, Filippis A, da Silva I . Zika virus infection-associated acute transient polyneuritis. Neurology. 2017; 88(24):2330-2332. DOI: 10.1212/WNL.0000000000004026. View

Mlakar J, Korva M, Tul N, Popovic M, Poljsak-Prijatelj M, Mraz J . Zika Virus Associated with Microcephaly. N Engl J Med. 2016; 374(10):951-8. DOI: 10.1056/NEJMoa1600651. View

Musso D, Gubler D . Zika Virus. Clin Microbiol Rev. 2016; 29(3):487-524. PMC: 4861986. DOI: 10.1128/CMR.00072-15. View

Paz-Bailey G, Rosenberg E, Doyle K, Munoz-Jordan J, Santiago G, Klein L . Persistence of Zika Virus in Body Fluids - Final Report. N Engl J Med. 2017; 379(13):1234-1243. PMC: 5831142. DOI: 10.1056/NEJMoa1613108. View

Palacios E, Clavijo-Prado C, Ruiz A, Arias Antun A, Julian Duran E . Longitudinal extensive transverse myelitis and Zika virus: A diagnostic challenge in a hospital in Colombia. Neurologia (Engl Ed). 2016; 34(3):204-206. DOI: 10.1016/j.nrl.2016.08.006. View

Gould E, Solomon T . Pathogenic flaviviruses. Lancet. 2008; 371(9611):500-9. DOI: 10.1016/S0140-6736(08)60238-X. View

10.

Massad E, Tan S, Khan K, Wilder-Smith A . Estimated Zika virus importations to Europe by travellers from Brazil. Glob Health Action. 2016; 9:31669. PMC: 4871896. DOI: 10.3402/gha.v9.31669. View

11.

Teng Y, Bi D, Xie G, Jin Y, Huang Y, Lin B . Model-informed risk assessment for Zika virus outbreaks in the Asia-Pacific regions. J Infect. 2017; 74(5):484-491. DOI: 10.1016/j.jinf.2017.01.015. View

12.

Roth W, Tyshkov C, Thakur K, Vargas W . Encephalomyelitis Following Definitive Zika Virus Infection. Neurol Neuroimmunol Neuroinflamm. 2017; 4(4):e349. PMC: 5413959. DOI: 10.1212/NXI.0000000000000349. View

13.

Willison H, Jacobs B, van Doorn P . Guillain-Barré syndrome. Lancet. 2016; 388(10045):717-27. DOI: 10.1016/S0140-6736(16)00339-1. View

14.

Nascimento O, da Silva I . Guillain-Barré syndrome and Zika virus outbreaks. Curr Opin Neurol. 2017; 30(5):500-507. DOI: 10.1097/WCO.0000000000000471. View

15.

Niemeyer B, Niemeyer R, Borges R, Marchiori E . Acute Disseminated Encephalomyelitis Following Zika Virus Infection. Eur Neurol. 2016; 77(1-2):45-46. DOI: 10.1159/000453396. View

16.

Solomon T . Flavivirus encephalitis. N Engl J Med. 2004; 351(4):370-8. DOI: 10.1056/NEJMra030476. View

17.

Cumberworth S, Barrie J, Cunningham M, de Figueiredo D, Schultz V, Wilder-Smith A . Zika virus tropism and interactions in myelinating neural cell cultures: CNS cells and myelin are preferentially affected. Acta Neuropathol Commun. 2017; 5(1):50. PMC: 5481922. DOI: 10.1186/s40478-017-0450-8. View

18.

Mehta R, Nascimento Soares C, Medialdea-Carrera R, Ellul M, da Silva M, Rosala-Hallas A . The spectrum of neurological disease associated with Zika and chikungunya viruses in adults in Rio de Janeiro, Brazil: A case series. PLoS Negl Trop Dis. 2018; 12(2):e0006212. PMC: 5837186. DOI: 10.1371/journal.pntd.0006212. View

19.

Leonhard S, Munts A, van der Eijk A, Jacobs B . Acute-onset chronic inflammatory demyelinating polyneuropathy after Zika virus infection. J Neurol Neurosurg Psychiatry. 2017; 89(10):1118-1119. DOI: 10.1136/jnnp-2017-317346. View

20.

Yuki N, Susuki K, Koga M, Nishimoto Y, Odaka M, Hirata K . Carbohydrate mimicry between human ganglioside GM1 and Campylobacter jejuni lipooligosaccharide causes Guillain-Barre syndrome. Proc Natl Acad Sci U S A. 2004; 101(31):11404-9. PMC: 509213. DOI: 10.1073/pnas.0402391101. View