Radiation-induced Neuropathic Pain Successfully Treated with Systemic Lidocaine Administration

Overview

Journal J Pain Res

Publisher Dove Medical Press

Date 2018 Mar 29

PMID 29588612

Citations 6

Authors

A Ram Doo

Yu Seob Shin

Seonwoo Yoo

Jong Kwan Park

Affiliations

Soon will be listed here.

Abstract

Radiation-induced neuropathic pain is a rare but devastating complication following cancer treatment. It is often progressive, refractory to conservative treatment, and sometimes irreversible. The exact mechanism of radiation-induced neuropathic pain is unknown, but it is associated with perineural fibrosis, atrophy, and ischemia. Systemic administration of local anesthetics is known to be effective for various acute and chronic painful diseases, such as neuropathic pain, as well as inflammatory and nociceptive pains. We report a patient with generalized radiation-induced neuropathic pain successfully treated with systemic lidocaine administration.

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