Galectin-3 in Atrial Fibrillation: Mechanisms and Therapeutic Implications

Overview

Journal Int J Mol Sci

Publisher MDPI

Specialties Biochemistry
Chemistry
Molecular Biology

Date 2018 Mar 29

PMID 29587379

Citations 28

Authors

Nicolas Clementy

Eric Piver

Arnaud Bisson

Clementine Andre

Anne Bernard

Bertrand Pierre

Laurent Fauchier

Dominique Babuty

Affiliations

Soon will be listed here.

Abstract

Maintenance of atrial fibrillation is a complex mechanism, including extensive electrical and structural remodeling of the atria which involves progressive fibrogenesis. Galectin-3 is a biomarker of fibrosis, and, thus, may be involved in atrial remodeling in atrial fibrillation patients. We review the role of galectin-3 in AF mechanisms and its potential therapeutic implications.

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