Out of Water: The Origin and Early Diversification of Plant -Genes

Overview

Journal Plant Physiol

Specialty Physiology

Date 2018 Mar 23

PMID 29563207

Citations 63

Authors

Yuxia Gao

Wenqiang Wang

Tian Zhang

Zhen Gong

Huayao Zhao

Guan-Zhu Han

Affiliations

Soon will be listed here.

Abstract

During plant-pathogen interactions, plants use intracellular proteins with nucleotide-binding site and Leu-rich repeat (NBS-LRR) domains to detect pathogens. NBS-LRR proteins represent a major class of plant disease resistance genes (-genes). Whereas -genes have been well characterized in angiosperms, little is known about their origin and early diversification. Here, we perform comprehensive evolutionary analyses of -genes in plants and report the identification of -genes in basal-branching streptophytes, including charophytes, liverworts, and mosses. Phylogenetic analyses suggest that plant -genes originated in charophytes and R-proteins diversified into TIR-NBS-LRR proteins and non-TIR-NBS-LRR proteins in charophytes. Moreover, we show that plant R-proteins evolved in a modular fashion through frequent gain or loss of protein domains. Most of the -genes in basal-branching streptophytes underwent adaptive evolution, indicating an ancient involvement of -genes in plant-pathogen interactions. Our findings provide novel insights into the origin and evolution of -genes and the mechanisms underlying colonization of terrestrial environments by plants.

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