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Pegylated Interferon Alfa-2a and Hydroxyurea in Polycythemia Vera and Essential Thrombocythemia: Differential Cellular and Molecular Responses

Overview
Journal Leukemia
Specialties Hematology
Oncology
Date 2018 Mar 21
PMID 29556018
Citations 12
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References
1.
Liu E, Jelinek J, Pastore Y, Guan Y, Prchal J, Prchal J . Discrimination of polycythemias and thrombocytoses by novel, simple, accurate clonality assays and comparison with PRV-1 expression and BFU-E response to erythropoietin. Blood. 2003; 101(8):3294-301. DOI: 10.1182/blood-2002-07-2287. View

2.
Nussenzveig R, Swierczek S, Jelinek J, Gaikwad A, Liu E, Verstovsek S . Polycythemia vera is not initiated by JAK2V617F mutation. Exp Hematol. 2007; 35(1):32-8. DOI: 10.1016/j.exphem.2006.11.012. View

3.
Gaikwad A, Nussenzveig R, Liu E, Gottshalk S, Chang K, Prchal J . In vitro expansion of erythroid progenitors from polycythemia vera patients leads to decrease in JAK2 V617F allele. Exp Hematol. 2007; 35(4):587-95. PMC: 1931508. DOI: 10.1016/j.exphem.2006.12.007. View

4.
Kiladjian J, Cassinat B, Chevret S, Turlure P, Cambier N, Roussel M . Pegylated interferon-alfa-2a induces complete hematologic and molecular responses with low toxicity in polycythemia vera. Blood. 2008; 112(8):3065-72. DOI: 10.1182/blood-2008-03-143537. View

5.
Moliterno A, Williams D, Rogers O, Isaacs M, Spivak J . Phenotypic variability within the JAK2 V617F-positive MPD: roles of progenitor cell and neutrophil allele burdens. Exp Hematol. 2008; 36(11):1480-6. PMC: 2600434. DOI: 10.1016/j.exphem.2008.05.006. View