Artificial Saliva and Its Use in Biological Experiments

Examination of dental materials and their properties at the initial stage of the digestive process requires the development of conditions that mimic the environment of the oral cavity. One of the main components of this area is saliva, where many reactions occur under natural conditions. Human saliva is an important physiological fluid that is essential for the maintenance of good oral health and of the entire human body; it is the place where digestion begins and thus contributes to the supply of those nutrients and health-promoting substances that are essential to the body but may also cause release of potential toxins. Thereby, the main aim of the study was to review the use of artificial saliva models in the context of stomatological and biological research. Biological studies have shown that the amount of biologically active substances in biological material is not the same as their quantity released under the conditions of the human digestive system and thus bioavailable to it. These results show that tables of active ingredients in drugs and food stuffs do not present their actual usefulness and availability to the human body.