Effectiveness of Pneumococcal and Influenza Vaccines to Prevent Serious Health Complications in Adults with Chronic Liver Disease: a Protocol for a Systematic Review

Overview

Journal BMJ Open

Specialty General Medicine

Date 2018 Mar 18

PMID 29549199

Citations 4

Authors

Suvi Harmala

Constantinos Parisinos

Laura Shallcross

Alastair OBrien

Andrew Hayward

Affiliations

Soon will be listed here.

Abstract

Introduction: In advanced chronic liver disease, diseases caused by common bacteria or influenza virus put people at an increased risk of serious health complications and death. The effectiveness of the available vaccines in reducing the risk of poor health outcomes, however, is less clear.

Methods And Analysis: We will search Medline (Ovid), Embase (Ovid), PubMed and Cochrane Central Register of Controlled Trials for published reports on randomised controlled trials and observational studies on the effectiveness of pneumococcal and influenza vaccines in people with chronic liver disease. Two independent reviewers will screen the studies for eligibility, extract data and assess study quality and risk of bias. Random effects meta-analyses will be performed as appropriate.

Ethics And Dissemination: Formal ethical approval is not required, as no primary data will be collected for this study. We will publish results of this study in relevant peer-reviewed medical journal or journals. Where possible, the study results will also be presented as posters or talks at relevant medical conferences and meetings.

Prospero Registration Number: CRD42017067277.

Citing Articles

Vaccination in liver diseases and liver Transplantation: Recommendations, implications and opportunities in the post-covid era.

Ballester M, Jalan R, Mehta G JHEP Rep. 2023; :100776.

PMID: 37360567 PMC: 10241163. DOI: 10.1016/j.jhepr.2023.100776.

Recommendations of the Italian society for infectious and tropical diseases (SIMIT) for adult vaccinations.

Andreoni M, Sticchi L, Nozza S, Sarmati L, Gori A, Tavio M Hum Vaccin Immunother. 2021; 17(11):4265-4282.

PMID: 34524945 PMC: 8828129. DOI: 10.1080/21645515.2021.1971473.

Influenza A virus infection induces liver injury in mice.

Zhang S, Hu B, Xu J, Ren Q, Wang L, Wang S Microb Pathog. 2019; 137:103736.

PMID: 31505263 PMC: 7125922. DOI: 10.1016/j.micpath.2019.103736.

Effectiveness of influenza vaccines in adults with chronic liver disease: a systematic review and meta-analysis.

Harmala S, Parisinos C, Shallcross L, OBrien A, Hayward A BMJ Open. 2019; 9(9):e031070.

PMID: 31494620 PMC: 6731888. DOI: 10.1136/bmjopen-2019-031070.

References

van Hoek A, Andrews N, Waight P, Stowe J, Gates P, George R . The effect of underlying clinical conditions on the risk of developing invasive pneumococcal disease in England. J Infect. 2012; 65(1):17-24. DOI: 10.1016/j.jinf.2012.02.017. View

Moher D, Liberati A, Tetzlaff J, Altman D . Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. Ann Intern Med. 2009; 151(4):264-9, W64. DOI: 10.7326/0003-4819-151-4-200908180-00135. View

Kastner M, Wilczynski N, Walker-Dilks C, McKibbon K, Haynes B . Age-specific search strategies for Medline. J Med Internet Res. 2007; 8(4):e25. PMC: 1794003. DOI: 10.2196/jmir.8.4.e25. View

Guyatt G, Oxman A, Vist G, Kunz R, Falck-Ytter Y, Alonso-Coello P . GRADE: an emerging consensus on rating quality of evidence and strength of recommendations. BMJ. 2008; 336(7650):924-6. PMC: 2335261. DOI: 10.1136/bmj.39489.470347.AD. View

Hassner A, Kletter Y, Shlag D, Yedvab M, Aronson M, SHIBOLET S . Impaired monocyte function in liver cirrhosis. Br Med J (Clin Res Ed). 1981; 282(6272):1262-3. PMC: 1505383. DOI: 10.1136/bmj.282.6272.1262. View

OBrien A, Fullerton J, Massey K, Auld G, Sewell G, James S . Immunosuppression in acutely decompensated cirrhosis is mediated by prostaglandin E2. Nat Med. 2014; 20(5):518-23. PMC: 5369639. DOI: 10.1038/nm.3516. View

Pebody R, Leino T, Nohynek H, Hellenbrand W, Salmaso S, Ruutu P . Pneumococcal vaccination policy in Europe. Euro Surveill. 2017; 10(9):11-12. DOI: 10.2807/esm.10.09.00564-en. View

Kanitz E, Wu L, Giambi C, Strikas R, Levy-Bruhl D, Stefanoff P . Variation in adult vaccination policies across Europe: an overview from VENICE network on vaccine recommendations, funding and coverage. Vaccine. 2012; 30(35):5222-8. DOI: 10.1016/j.vaccine.2012.06.012. View

Rajkovic I, Williams R . Abnormalities of neutrophil phagocytosis, intracellular killing and metabolic activity in alcoholic cirrhosis and hepatitis. Hepatology. 1986; 6(2):252-62. DOI: 10.1002/hep.1840060217. View

10.

Shamseer L, Moher D, Clarke M, Ghersi D, Liberati A, Petticrew M . Preferred reporting items for systematic review and meta-analysis protocols (PRISMA-P) 2015: elaboration and explanation. BMJ. 2015; 350:g7647. DOI: 10.1136/bmj.g7647. View

11.

Polakos N, Cornejo J, Murray D, Wright K, Treanor J, Crispe I . Kupffer cell-dependent hepatitis occurs during influenza infection. Am J Pathol. 2006; 168(4):1169-78. PMC: 1606556. DOI: 10.2353/ajpath.2006.050875. View

12.

Fierer J, Finley F . Deficient serum bactericidal activity against Escherichia coli in patients with cirrhosis of the liver. J Clin Invest. 1979; 63(5):912-921. PMC: 372032. DOI: 10.1172/JCI109391. View

13.

Duchini A, Viernes M, Nyberg L, Hendry R, Pockros P . Hepatic decompensation in patients with cirrhosis during infection with influenza A. Arch Intern Med. 2000; 160(1):113-5. DOI: 10.1001/archinte.160.1.113. View

14.

Kirkham J, Dwan K, Altman D, Gamble C, Dodd S, Smyth R . The impact of outcome reporting bias in randomised controlled trials on a cohort of systematic reviews. BMJ. 2010; 340:c365. DOI: 10.1136/bmj.c365. View

15.

Gil-Prieto R, Pascual-Garcia R, Walter S, Alvaro-Meca A, Gil-de-Miguel A . Risk of hospitalization due to pneumococcal disease in adults in Spain. The CORIENNE study. Hum Vaccin Immunother. 2016; 12(7):1900-5. PMC: 4964827. DOI: 10.1080/21645515.2016.1143577. View

16.

Blachier M, Leleu H, Peck-Radosavljevic M, Valla D, Roudot-Thoraval F . The burden of liver disease in Europe: a review of available epidemiological data. J Hepatol. 2013; 58(3):593-608. DOI: 10.1016/j.jhep.2012.12.005. View

17.

Puig-Barbera J, Natividad-Sancho A, Trushakova S, Sominina A, Pisareva M, Ciblak M . Epidemiology of Hospital Admissions with Influenza during the 2013/2014 Northern Hemisphere Influenza Season: Results from the Global Influenza Hospital Surveillance Network. PLoS One. 2016; 11(5):e0154970. PMC: 4873033. DOI: 10.1371/journal.pone.0154970. View

18.

Van Kerkhove M, Vandemaele K, Shinde V, Jaramillo-Gutierrez G, Koukounari A, Donnelly C . Risk factors for severe outcomes following 2009 influenza A (H1N1) infection: a global pooled analysis. PLoS Med. 2011; 8(7):e1001053. PMC: 3130021. DOI: 10.1371/journal.pmed.1001053. View

19.

Chalmers J, Campling J, Dicker A, Woodhead M, Madhava H . A systematic review of the burden of vaccine preventable pneumococcal disease in UK adults. BMC Pulm Med. 2016; 16(1):77. PMC: 4864929. DOI: 10.1186/s12890-016-0242-0. View