Pancreas 3D Organoids: Current and Future Aspects As a Research Platform for Personalized Medicine in Pancreatic Cancer

Overview

Journal Cell Mol Gastroenterol Hepatol

Specialty Gastroenterology

Date 2018 Mar 16

PMID 29541683

Citations 54

Authors

Leticia Moreira

Basil Bakir

Priya Chatterji

Zahra Dantes

Maximilian Reichert

Anil K Rustgi

Affiliations

Soon will be listed here.

Abstract

Pancreatic ductal adenocarcinoma is one of the most aggressive forms of cancer, and the third leading cause of cancer-related mortality in the United States. Although important advances have been made in the last decade, the mortality rate of pancreatic ductal adenocarcinoma has not changed appreciably. This review summarizes a rapidly emerging model of pancreatic cancer research, focusing on 3-dimensional organoids as a powerful tool for several applications, but above all, representing a step toward personalized medicine.

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