Seasonal Reproduction in Vertebrates: Melatonin Synthesis, Binding, and Functionality Using Tinbergen's Four Questions

Overview

Journal Molecules

Publisher MDPI

Specialty Biology

Date 2018 Mar 14

PMID 29534047

Citations 18

Authors

Dax viviD

George E Bentley

Affiliations

Soon will be listed here.

Abstract

One of the many functions of melatonin in vertebrates is seasonal reproductive timing. Longer nights in winter correspond to an extended duration of melatonin secretion. The purpose of this review is to discuss melatonin synthesis, receptor subtypes, and function in the context of seasonality across vertebrates. We conclude with Tinbergen's Four Questions to create a comparative framework for future melatonin research in the context of seasonal reproduction.

Citing Articles

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The Photoperiod-Driven Cyclical Secretion of Pineal Melatonin Regulates Seasonal Reproduction in Geese ().

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References

Maitra S, Hasan K . The Role of Melatonin as a Hormone and an Antioxidant in the Control of Fish Reproduction. Front Endocrinol (Lausanne). 2016; 7:38. PMC: 4854901. DOI: 10.3389/fendo.2016.00038. View

Hong L, Hong W, Zhu W, Shi Q, You X, Chen S . Cloning and expression of melatonin receptors in the mudskipper Boleophthalmus pectinirostris: their role in synchronizing its semilunar spawning rhythm. Gen Comp Endocrinol. 2013; 195:138-50. DOI: 10.1016/j.ygcen.2013.11.004. View

Ohta M, Kadota C, Konishi H . A role of melatonin in the initial stage of photoperiodism in the Japanese quail. Biol Reprod. 1989; 40(5):935-41. DOI: 10.1095/biolreprod40.5.935. View

Gauer F, Schuster C, Poirel V, Pevet P, Masson-Pevet M . Cloning experiments and developmental expression of both melatonin receptor Mel1A mRNA and melatonin binding sites in the Syrian hamster suprachiasmatic nuclei. Brain Res Mol Brain Res. 1998; 60(2):193-202. DOI: 10.1016/s0169-328x(98)00177-6. View

Panzica G, Fraschini F, Aste N, Lucini V, Viglietti-Panzica C, Cozzi B . The density of melatonin receptors is dependent upon the prevailing photoperiod in the Japanese quail (Coturnix japonica). Neurosci Lett. 1994; 173(1-2):111-4. DOI: 10.1016/0304-3940(94)90161-9. View

Bentley G, Ubuka T, McGuire N, Chowdhury V, Morita Y, Yano T . Gonadotropin-inhibitory hormone and its receptor in the avian reproductive system. Gen Comp Endocrinol. 2007; 156(1):34-43. DOI: 10.1016/j.ygcen.2007.10.003. View

Boulos Z, Macchi M . Season- and latitude-dependent effects of simulated twilights on circadian entrainment. J Biol Rhythms. 2005; 20(2):132-44. DOI: 10.1177/0748730404272907. View

Kriegsfeld L, Ubuka T, Bentley G, Tsutsui K . Seasonal control of gonadotropin-inhibitory hormone (GnIH) in birds and mammals. Front Neuroendocrinol. 2014; 37:65-75. PMC: 4405439. DOI: 10.1016/j.yfrne.2014.12.001. View

Cazamea-Catalan D, Besseau L, Falcon J, Magnanou E . The timing of Timezyme diversification in vertebrates. PLoS One. 2014; 9(12):e112380. PMC: 4259306. DOI: 10.1371/journal.pone.0112380. View

10.

Sockman K, Sharp P, Schwabl H . Orchestration of avian reproductive effort: an integration of the ultimate and proximate bases for flexibility in clutch size, incubation behaviour, and yolk androgen deposition. Biol Rev Camb Philos Soc. 2006; 81(4):629-66. DOI: 10.1017/S1464793106007147. View

11.

Foulkes N, Borjigin J, Snyder S, Sassone-Corsi P . Rhythmic transcription: the molecular basis of circadian melatonin synthesis. Trends Neurosci. 1997; 20(10):487-92. DOI: 10.1016/s0166-2236(97)01109-0. View

12.

Reiter R, Rosales-Corral S, Manchester L, Tan D . Peripheral reproductive organ health and melatonin: ready for prime time. Int J Mol Sci. 2013; 14(4):7231-72. PMC: 3645684. DOI: 10.3390/ijms14047231. View

13.

Johnston J, Messager S, Barrett P, Hazlerigg D . Melatonin action in the pituitary: neuroendocrine synchronizer and developmental modulator?. J Neuroendocrinol. 2003; 15(4):405-8. DOI: 10.1046/j.1365-2826.2003.00972.x. View

14.

Weaver D, Stehle J, Stopa E, Reppert S . Melatonin receptors in human hypothalamus and pituitary: implications for circadian and reproductive responses to melatonin. J Clin Endocrinol Metab. 1993; 76(2):295-301. DOI: 10.1210/jcem.76.2.8381796. View

15.

Rzasa J, Ewy Z . Effect of vasotocin and oxytocin on oviposition in the hen. J Reprod Fertil. 1970; 21(3):549-50. DOI: 10.1530/jrf.0.0210549. View

16.

Sumaya I, Masana M, Dubocovich M . The antidepressant-like effect of the melatonin receptor ligand luzindole in mice during forced swimming requires expression of MT2 but not MT1 melatonin receptors. J Pineal Res. 2005; 39(2):170-7. DOI: 10.1111/j.1600-079X.2005.00233.x. View

17.

Maitra S, Chattoraj A, Mukherjee S, Moniruzzaman M . Melatonin: a potent candidate in the regulation of fish oocyte growth and maturation. Gen Comp Endocrinol. 2012; 181:215-22. DOI: 10.1016/j.ygcen.2012.09.015. View

18.

Teerawatanasuk N, CARR L . CBF/NF-Y activates transcription of the human tryptophan hydroxylase gene through an inverted CCAAT box. Brain Res Mol Brain Res. 1998; 55(1):61-70. DOI: 10.1016/s0169-328x(97)00364-1. View

19.

Gill S, Lavoie H, Bo-Abbas Y, Hall J . Negative feedback effects of gonadal steroids are preserved with aging in postmenopausal women. J Clin Endocrinol Metab. 2002; 87(5):2297-302. DOI: 10.1210/jcem.87.5.8510. View

20.

Aste N, Cozzi B, Stankov B, Panzica G . Sexual differences and effect of photoperiod on melatonin receptor in avian brain. Microsc Res Tech. 2001; 55(1):37-47. DOI: 10.1002/jemt.1154. View