QseC Mediates Osmotic Stress Resistance and Biofilm Formation in

Overview

Journal Front Microbiol

Specialty Microbiology

Date 2018 Mar 1

PMID 29487590

Citations 20

Authors

Lvqin He

Ke Dai

Xintian Wen

LingQiang Ding

Sanjie Cao

Xiaobo Huang

Rui Wu

Qin Zhao

Yong Huang

Qigui Yan

Xiaoping Ma

Xinfeng Han

Yiping Wen

Affiliations

Soon will be listed here.

Abstract

is known as a commensal organism discovered in the upper respiratory tract of swine where the pathogenic bacteria survive in various adverse environmental stress. QseC, a histidine protein kinase of the two-component regulatory systems CheY/QseC, is involved in the environmental adaptation in bacteria. To investigate the role of QseC in coping with the adverse environment stresses and survive in the host, we constructed a mutant of serovar 13 strain (Δ), MY1902. In this study, we found that QseC was involved in stress tolerance of , by the Δ exhibited a decreased resistance to osmotic pressure, oxidative stress, and heat shock. Moreover, the Δ weakened the ability to take up iron and biofilm formation. We also found that the QseC participate in sensing the epinephrine in environment to regulate the density of .

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