Chemotherapy-Associated Endometrial Atypia: A Potential Diagnostic Pitfall

Cytotoxic chemotherapy, typically as a component of a multimodal approach, is a standard of patient care for numerous malignancies. Chemotherapy-associated cytologic alterations in otherwise normal tissues have been reported at several anatomic sites. We describe in this article distinctive cytologic alterations of the endometrium, including severe severe cytologic atypia, that was attributed to chemotherapy.