Different Contributions of Nonmuscle Myosin IIA and IIB to the Organization of Stress Fiber Subtypes in Fibroblasts

Overview

Journal Mol Biol Cell

Specialties Cell Biology
Molecular Biology

Date 2018 Feb 23

PMID 29467250

Citations 14

Authors

Masahiro Kuragano

Taro Q P Uyeda

Keiju Kamijo

Yota Murakami

Masayuki Takahashi

Affiliations

Soon will be listed here.

Abstract

We demonstrated that myosin IIA and IIB are essential for the formation of transverse arcs and ventral stress fibers, respectively. Furthermore, we illustrated the roles of both isoforms in lamellar flattening and also raised the possibility that actin filaments in ventral stress fibers are in a stretched conformation.

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