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Bax Inhibitor-1 Protects from Nonalcoholic Steatohepatitis by Limiting Inositol-requiring Enzyme 1 Alpha Signaling in Mice

Abstract

Conclusion: Targeting IRE1α-dependent NLRP3 inflammasome signaling with pharmacological agents or by BI-1 may represent a tangible therapeutic strategy for NASH. (Hepatology 2018).

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