Family-Based Interventions Targeting Improvements in Health and Family Outcomes of Children and Adolescents with Type 1 Diabetes: a Systematic Review

Overview

Journal Curr Diab Rep

Publisher Current Science

Specialty Endocrinology

Date 2018 Feb 20

PMID 29457190

Citations 18

Authors

Marissa A Feldman

Lindsay M Anderson

Jenna B Shapiro

Aneta M Jedraszko

Meredyth Evans

Lindsey E G Weil

Kimberly P Garza

Jill Weissberg-Benchell

Affiliations

Soon will be listed here.

Abstract

Purpose Of Review: A systematic review was conducted of family-based interventions to improve glycemic control, adherence, and psychosocial outcomes in children and adolescents with type 1 diabetes (T1D). Electronic databases were searched for randomized controlled trials (RCTs) published since the seminal Diabetes Control and Compliance Trial (DCCT). Interventions are summarized and findings reviewed to help guide clinical practice and future research.

Recent Findings: Twenty-five RCTs are reviewed. The majority of studies (n = 15) focused on interventions targeting both children and adolescents and their caregivers and were delivered in diabetes clinics, outpatient settings, mental health clinics, or participants' homes. Family-based interventions for youth with T1D appear effective at improving diabetes and family-centered outcomes. Additional research is needed to examine the pathways to improvement in glycemic control, as outcomes were mixed. Future research should also involve measures beyond HbA1c given new markers for sustained health improvement and outcomes are being explored.

Citing Articles

Health Equity Intervention for Youth with Type 1 Diabetes and High Social Risk.

Stover-Kempers S, Torres K, Barry-Menkhaus S, Jenisch C, Spiro K, Harris M Children (Basel). 2025; 12(2).

PMID: 40003302 PMC: 11854909. DOI: 10.3390/children12020200.

The role of mental health nursing in pediatric hematology/oncology - Part 3: Evaluating feasibility, acceptability, and appreciation.

Bernier P, Desjardins L, Charette M, Harnois J, Poirier E, Daigle K Can Oncol Nurs J. 2024; 34(4):505-522.

PMID: 39507546 PMC: 11537429. DOI: 10.5737/23688076344514.

Meeting the Needs of Emerging Adults With Type 1 Diabetes Living in a Rural Area With Mobile Health Interventions: Focus Group Study.

Carcone A, Holtz B, Reardon M, Vesey D, Ellis D, Parks M JMIR Form Res. 2024; 8:e55650.

PMID: 39110496 PMC: 11339569. DOI: 10.2196/55650.

Moderating Effect of Depression on Glycemic Control in an eHealth Intervention Among Black Youth With Type 1 Diabetes: Findings From a Multicenter Randomized Controlled Trial.

Ellis D, Carcone A, Templin T, Evans M, Weissberg-Benchell J, Buggs-Saxton C JMIR Diabetes. 2024; 9:e55165.

PMID: 38593428 PMC: 11040442. DOI: 10.2196/55165.

Self-care activities in pediatric patients with type 1 diabetes mellitus.

Smudja M, Milenkovic T, Minakovic I, Zdravkovic V, Javorac J, Milutinovic D PLoS One. 2024; 19(3):e0300055.

PMID: 38442115 PMC: 10914259. DOI: 10.1371/journal.pone.0300055.

References

Dougherty G, Schiffrin A, White D, Soderstrom L, Sufrategui M . Home-based management can achieve intensification cost-effectively in type I diabetes. Pediatrics. 1999; 103(1):122-8. DOI: 10.1542/peds.103.1.122. View

Hilliard M, Holmes C, Chen R, Maher K, Robinson E, Streisand R . Disentangling the roles of parental monitoring and family conflict in adolescents' management of type 1 diabetes. Health Psychol. 2012; 32(4):388-396. PMC: 3811134. DOI: 10.1037/a0027811. View

Duke D, Wagner D, Ulrich J, Freeman K, Harris M . Videoconferencing for Teens With Diabetes: Family Matters. J Diabetes Sci Technol. 2016; 10(4):816-23. PMC: 4928237. DOI: 10.1177/1932296816642577. View

Ellis D, Templin T, Naar-King S, Frey M, Cunningham P, Podolski C . Multisystemic therapy for adolescents with poorly controlled type I diabetes: Stability of treatment effects in a randomized controlled trial. J Consult Clin Psychol. 2007; 75(1):168-74. DOI: 10.1037/0022-006X.75.1.168. View

Ryden O, Nevander L, Johnsson P, Hansson K, Kronvall P, Sjoblad S . Family therapy in poorly controlled juvenile IDDM: effects on diabetic control, self-evaluation and behavioural symptoms. Acta Paediatr. 1994; 83(3):285-91. DOI: 10.1111/j.1651-2227.1994.tb18096.x. View

Holmes C, Chen R, Mackey E, Grey M, Streisand R . Randomized clinical trial of clinic-integrated, low-intensity treatment to prevent deterioration of disease care in adolescents with type 1 diabetes. Diabetes Care. 2014; 37(6):1535-43. PMC: 4030089. DOI: 10.2337/dc13-1053. View

Ellis D, Naar-King S, Templin T, Frey M, Cunningham P, Sheidow A . Multisystemic therapy for adolescents with poorly controlled type 1 diabetes: reduced diabetic ketoacidosis admissions and related costs over 24 months. Diabetes Care. 2008; 31(9):1746-7. PMC: 2518338. DOI: 10.2337/dc07-2094. View

McBroom L, Enriquez M . Review of family-centered interventions to enhance the health outcomes of children with type 1 diabetes. Diabetes Educ. 2009; 35(3):428-38. DOI: 10.1177/0145721709332814. View

Hsin O, La Greca A, Valenzuela J, Moine C, Delamater A . Adherence and glycemic control among Hispanic youth with type 1 diabetes: role of family involvement and acculturation. J Pediatr Psychol. 2009; 35(2):156-66. PMC: 2821010. DOI: 10.1093/jpepsy/jsp045. View

10.

Ellis D, Naar-King S, Chen X, Moltz K, Cunningham P, Idalski-Carcone A . Multisystemic therapy compared to telephone support for youth with poorly controlled diabetes: findings from a randomized controlled trial. Ann Behav Med. 2012; 44(2):207-15. PMC: 3443313. DOI: 10.1007/s12160-012-9378-1. View

11.

Wysocki T, Harris M, Buckloh L, Mertlich D, Lochrie A, Taylor A . Effects of behavioral family systems therapy for diabetes on adolescents' family relationships, treatment adherence, and metabolic control. J Pediatr Psychol. 2006; 31(9):928-38. DOI: 10.1093/jpepsy/jsj098. View

12.

Forsander G, Persson B, Sundelin J, Berglund E, Snellman K, HELLSTROM R . Metabolic control in children with insulin-dependent diabetes mellitus 5 y after diagnosis. Early detection of patients at risk for poor metabolic control. Acta Paediatr. 1998; 87(8):857-64. DOI: 10.1080/080352598750013635. View

13.

Katz M, Volkening L, Butler D, Anderson B, Laffel L . Family-based psychoeducation and Care Ambassador intervention to improve glycemic control in youth with type 1 diabetes: a randomized trial. Pediatr Diabetes. 2013; 15(2):142-50. PMC: 3915039. DOI: 10.1111/pedi.12065. View

14.

Wysocki T, Harris M, Buckloh L, Mertlich D, Lochrie A, Mauras N . Randomized trial of behavioral family systems therapy for diabetes: maintenance of effects on diabetes outcomes in adolescents. Diabetes Care. 2007; 30(3):555-60. DOI: 10.2337/dc06-1613. View

15.

Laffel L, Vangsness L, Connell A, Goebel-Fabbri A, Butler D, Anderson B . Impact of ambulatory, family-focused teamwork intervention on glycemic control in youth with type 1 diabetes. J Pediatr. 2003; 142(4):409-16. DOI: 10.1067/mpd.2003.138. View

16.

Murphy H, Wadham C, Hassler-Hurst J, Rayman G, Skinner T . Randomized trial of a diabetes self-management education and family teamwork intervention in adolescents with Type 1 diabetes. Diabet Med. 2012; 29(8):e249-54. DOI: 10.1111/j.1464-5491.2012.03683.x. View

17.

King P, Berg C, Butner J, Butler J, Wiebe D . Longitudinal trajectories of parental involvement in Type 1 diabetes and adolescents' adherence. Health Psychol. 2013; 33(5):424-32. PMC: 4766001. DOI: 10.1037/a0032804. View

18.

Ellis D, Frey M, Naar-King S, Templin T, Cunningham P, Cakan N . The effects of multisystemic therapy on diabetes stress among adolescents with chronically poorly controlled type 1 diabetes: findings from a randomized, controlled trial. Pediatrics. 2005; 116(6):e826-32. DOI: 10.1542/peds.2005-0638. View

19.

Anderson B, Brackett J, Ho J, Laffel L . An office-based intervention to maintain parent-adolescent teamwork in diabetes management. Impact on parent involvement, family conflict, and subsequent glycemic control. Diabetes Care. 1999; 22(5):713-21. DOI: 10.2337/diacare.22.5.713. View

20.

Hilliard M, Wu Y, Rausch J, Dolan L, Hood K . Predictors of deteriorations in diabetes management and control in adolescents with type 1 diabetes. J Adolesc Health. 2012; 52(1):28-34. PMC: 4467546. DOI: 10.1016/j.jadohealth.2012.05.009. View